Shimazaki (2003). Biology and clinical application of neural stem cells.

Wise Young · 12-23-2003, 10:23 AM

• Shimazaki T (2003). Biology and clinical application of neural stem cells. Horm Res. 60 Suppl 3: 1-9. Department of Physiology, Keio University School of Medicine, Tokyo, Japan; Core Research for Evolutional Science and Technology (CREST), Japan Science and Technology Corporation, Saitama, Japan. Neural stem cells, which exist in various regions of the CNS throughout the mammalian lifespan, can be expanded and induced to differentiate into neurons and glia in vitro and in vivo. Because of these characteristics, there has been increasing interest in the identification and characterization of neural stem cells and neural progenitor cells both for basic developmental biology studies and for therapeutic applications to the damaged brain. Transplantation of neural stem cells or their derivatives into a host brain and the proliferation and differentiation of endogenous stem cells by pharmacological manipulations are potential treatments for many neurodegenerative diseases and brain injuries, such as Parkinson's disease, brain ischemia and spinal cord injury. Continued progress in neural stem cell research is providing a new future for brain repair.

mattblan · 01-08-2004, 02:22 AM

Is the full text accessible? I tried to go through http://www.ncbi.nlm.nih.gov but it's members only. If every site is like that, how does anyone get information? Do they have to pay 1,000 membership fees every month, or what?

12-23-2003, 10:23 AM	#1
Wise Young Administrator Join Date: Jul 2001 Location: New Brunswick, NJ, USA Posts: 37,988	Shimazaki (2003). Biology and clinical application of neural stem cells. • Shimazaki T (2003). Biology and clinical application of neural stem cells. Horm Res. 60 Suppl 3: 1-9. Department of Physiology, Keio University School of Medicine, Tokyo, Japan; Core Research for Evolutional Science and Technology (CREST), Japan Science and Technology Corporation, Saitama, Japan. Neural stem cells, which exist in various regions of the CNS throughout the mammalian lifespan, can be expanded and induced to differentiate into neurons and glia in vitro and in vivo. Because of these characteristics, there has been increasing interest in the identification and characterization of neural stem cells and neural progenitor cells both for basic developmental biology studies and for therapeutic applications to the damaged brain. Transplantation of neural stem cells or their derivatives into a host brain and the proliferation and differentiation of endogenous stem cells by pharmacological manipulations are potential treatments for many neurodegenerative diseases and brain injuries, such as Parkinson's disease, brain ischemia and spinal cord injury. Continued progress in neural stem cell research is providing a new future for brain repair.

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01-08-2004, 02:22 AM	#2
mattblan Senior Member Join Date: Oct 2001 Location: N. California Posts: 1,148	Is the full text accessible? I tried to go through http://www.ncbi.nlm.nih.gov but it's members only. If every site is like that, how does anyone get information? Do they have to pay 1,000 membership fees every month, or what?