Stem Cell Articles - Page 363

manouli · 12-02-2009, 10:23 AM

New Report: Advances in the Stem Cell Industry: The Future Impact of Innovation

LONDON, December 1 /PRNewswire/ -- Global stem cell market sales reached $410 million in 2008, and will grow to $2.68 billion by 2012 according to a new report on http://www.companiesandmarkets.com.

Advances in the Stem Cell Industry: The Future Impact Of Innovation, And An Evaluation Of The Commercial Landscape

http://www.companiesandmarkets.com/r...CP03OFNH168616

An important milestone in the development of stem cell technology occurred in 2007, when researchers induced human cells into a stem cell state using defined genetic factors. These cells are now known as induced pluripotent stem (IPS) cells; they offer an alternative to using embryonic stem cells. This report takes the implications of IPS cells and other developments into account. Some essential technologies are already in place and stem-cell based therapies have already begun to appear in the marketplace. This has enabled the author to build market estimates based on emerging commercial realities. The stem cell market is already divided into three segments-cell-based treatments, umbilical cord blood banking, and the use of stem cells to evaluate the efficacy and safety of new drugs developed by other methods. Global sales reached $410 million in 2008, and will grow to $2.68 billion by 2012. This growth will reach a projected $5.1 billion in 2014, providing a realistic, and even cautious forecast of the commercial potential of these segments.

read...

http://twincities.bizjournals.com/tw.../12/01/UKTU027

manouli · 12-03-2009, 10:14 AM

ImmunoCellular Therapeutics Enters into Option Agreement with The University of Texas M. D. Anderson Cancer Center for a Novel Cancer Stem Cell Therapy

LOS ANGELES--(BUSINESS WIRE)--Dec 2, 2009 - ImmunoCellular Therapeutics, Ltd. (OTCBB: IMUC) (IMUC), a biotechnology company that is focused on the development of novel immune-based cancer therapies, announced today that it has entered into an option agreement with The University of Texas M. D. Anderson Cancer Center relating to an immunotherapy targeting cancer stem cells (CSCs) which has demonstrated in pre-clinical animal models significant abilities to target and destroy CSCs. This latest agreement bolsters the Company's portfolio of technologies targeting CSCs. This portfolio already features several promising therapies, including ICT-107, a dendritic cell based immunotherapy that recently completed a phase I study, and ICT-121, an off-the-shelf peptide targeting CSCs.

more...

http://www.medadnews.com/News/Index....ticleid=670522

kenf · 12-04-2009, 01:34 AM

Manouli for your dedaction to this tread and your other post on things going on , you should get a star by your ID. thank you , Ken

manouli · 12-04-2009, 05:27 PM

Quote:

Originally Posted by kenf

Manouli for your dedaction to this tread and your other post on things going on , you should get a star by your ID. thank you , Ken

kenf hi! Thank you so much you are so nice. Everyone here is so helpfull, and I am learning so much. I hope all of us will get cured, I believe we will.

manouli.

Norm · 12-04-2009, 06:02 PM

First New Embryonic Stem Cell Lines Approved for U.S. (Update3)

Dec. 2 (Bloomberg) -- Thirteen embryonic stem-cell lines were approved for use by U.S.-funded researchers today, the first of hundreds of cell colonies that may become available under new polices promised by President Barack Obama

http://www.bloomberg.com/apps/news?p...d=axgmWSy1i6vU

manouli · 12-04-2009, 06:46 PM

New Technology Captures Tumor Cells from the Bloodstream
Category: Laboratory News, Laboratory Pathology
Published: December 4 2009

Nano-technology Breakthrough May Prevent Cancers from Metastasizing

With the goal of removing tumor cells from the bloodstream, a biomedical engineering team at the University of Arkansas for Medical Sciences (UAMS) in Little Rock has discovered a non-invasive way to identify cancer and to capture tumor cells in the bloodstream. This landmark discovery, could dramatically improve early cancer diagnosis and prevent deadly metastasis. It could also provide a framework for a new type of diagnostic test that could detect metastatic cancer from a blood sample.

Led by Vladimir Zharov, Ph.D., D.Sc., Director of the UAMS Phillips Classic Laser and Nanomedicine Laboratory, the scientific team injected a cocktail of golden carbon nanotubes and magnetic nanoparticles with a special biological coating into the bloodstream to target circulating tumor cells. This allows a magnet attached to the skin above peripheral blood vessels to capture tumor cells, especially so-called “rolling cells.” This team published its findings in the Nov. 15, 2009 edition of Nature Nanotechnology.

more...

http://www.darkdaily.com/new-technol...loodstream-124

manouli · 12-04-2009, 06:50 PM

Public release date: 4-Dec-2009
[ Print | E-mail | Share ] [ Close Window ]

Contact: Dean Forbes
dforbes@fhcrc.org
206-667-2896
Fred Hutchinson Cancer Research Center

Cholesterol-lowering drugs also may protect stem cell transplant patients from GVHD

SEATTLE – Cholesterol-lowering drugs known as statins are among the most prescribed medicines in the U.S. Now a new study by researchers at Fred Hutchinson Cancer Research Center indicates that statins may protect stem cell transplant patients from one of the most serious complications of the life-saving cancer therapy: graft-versus-host disease, or GVHD. The findings are reported in the Nov. 4 first edition of the journal Blood.

In a retrospective study of 567 patients who underwent hematopoietic cell transplantation from matched sibling donors between 2001 and 2007, patients whose donors had been taking statins at the time of stem cell donation experienced no severe acute GVHD. About 15 percent of the stem cell donors in the study were taking statins at the time of transplant.

Normally, between 10 percent and 15 percent of transplant patients would be expected to develop severe acute GVHD, according to the study's senior author Marco Mielcarek, M.D., an assistant member of the Hutchinson Center's Clinical Research Division.

more....

http://www.eurekalert.org/pub_releas...-cda120409.php

manouli · 12-04-2009, 06:53 PM

Fri Dec 4 07:14:44 2009 Pacific Time

Stem Cells Battle for Space

BALTIMORE, Dec. 4 (AScribe Newswire) -- The body is a battle zone. Cells constantly compete with one another for space and dominance. Though the manner in which some cells win this competition is well known to be the survival of the fittest, how stem cells duke it out for space and survival is not as clear. A study on fruit flies published in the October 2 issue of Science by Johns Hopkins researchers describes how stem cells win this battle by literally sticking around.

"Our work exemplifies how one signal coordinately maintains two types of stem cells in a single niche, or microenvironment," says Erika Matunis, Ph.D., associate professor of cell biology at the Johns Hopkins School of Medicine. "What we found may emerge as common themes of mammalian stem cell niches as they become better characterized."

To tackle the stem cell competition quandary, the team looked at fruit fly testes where two different stem cells exist: germline stem cells which give rise to sperm, and somatic stem cells which develop into non-reproductive cell types.

more...

http://newswire.ascribe.org/cgi-bin/...=2009&public=0

manouli · 12-05-2009, 12:29 PM

Elections have consequences for stem cell research at the University of Michigan
December 4, 10:31 PMDetroit Science News ExaminerVince Lamb

Two issues decided in last year's general election have resulted in benefits for stem cell research in Michigan, especially at the University of Michigan.

First, the election of President Barack Obama, who promised to "restore science to its rightful place" in his Inaugural Address, led to a stimulus package that has so far awarded 342 grants totaling $206.4 million for scientific research at the University of Michigan. Among these awards are thirteen grants totaling $6.8 million from federal stimulus funds for stem cell research.

Second, the passage of Proposition 2 in November 2008 allowed the state of Michigan to relax restrictions on embryonic stem cells. While many of the stem-cell projects funded by stimulus money may still have been possible under the pre-2008 state law, they have been made easier under the new constitutional amendment. In a press release, Sean Morrison, director of the U-M Center for Stem Cell Biology, stated that the highly restrictive state laws had discouraged many stem cell researchers from pursuing embryonic stem cell research in the state.

"Proposal 2 is going to allow us to hire more people who work in the area of embryonic stem cells, and this NIH grant illustrates that the federal government will provide funding to fuel that expansion," Morrison said.

In addition to Morrison, who received a $744,000 stimulus grant from NIH to examine the potential of using human embryonic stem cells to develop a treatment for Hirschsprung disease, a birth defect in which the nervous system that regulates intestinal function does not develop properly, the following researchers receieved stimulus grants to study stem cells.

read....
http://www.examiner.com/x-31561-Detr...ty-of-Michigan

manouli · 12-06-2009, 11:07 AM

Multiple Sclerosis Patient Finds Hope Through Stem Cell Treatment

-Electromyogram (EMG) findings show improvement in conduction speed and latency

-RNL Bio's stem cell therapy demonstrates effective outcomes
SEOUL, Korea, Dec. 6 /PRNewswire/ -- RNL Bio Co., Ltd, (www.rnl.co.kr) a leading biopharmaceutical company specialized in adult stem cell therapeutics announced today that a 46-year-old female, Kang Sook Park's Multiple Sclerosis improved tremendously after receiving stem cell treatment. Park was suffering from MS (Multiple Sclerosis), an autoimmune disease that affects the central nervous system (brain and spinal cord).

Multiple Sclerosis is a disease in which the nerves of the central nervous system degenerate. MS can cause problems with muscle control and strength, vision, balance, feeling, and thinking. MS is caused by damage to the myelin sheath, the protective covering that surrounds nerve cells. When the myelin sheath is damaged, nerve impulses slow down or stop responding. From the many symptoms of MS, numbness or abnormal sensation in any area is predominant.

For the past 20 years, Park suffered from MS. For stem cell injection, she was admitted into Choyang Hospital of Regenerative Medicine in Yanji, China for three weeks. She received stem cells intravenously as well as intrathecally. The injections were given in five intervals -- a total of 1.2 billion cells.

more...

http://www.prnewswire.com/news-relea...-78625262.html

12-04-2009, 01:34 AM	#3623
kenf Senior Member Join Date: Mar 2005 Posts: 2,715	Manouli for your dedaction to this tread and your other post on things going on , you should get a star by your ID. thank you , Ken __________________ oh well

12-04-2009, 06:02 PM	#3625
Norm Senior Member Join Date: Jul 2001 Location: formally Boca Raton, FL, now Media, PA Posts: 1,411	First New Embryonic Stem Cell Lines Approved for U.S. (Update3) Dec. 2 (Bloomberg) -- Thirteen embryonic stem-cell lines were approved for use by U.S.-funded researchers today, the first of hundreds of cell colonies that may become available under new polices promised by President Barack Obama http://www.bloomberg.com/apps/news?p...d=axgmWSy1i6vU __________________ "Some people say that, the longer you go the better it gets the more you get used to it, I'm actually finding the opposite is true." -Christopher Reeve on his Paralysis

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12-02-2009, 10:23 AM	#3621
manouli Senior Member Join Date: Nov 2004 Location: florida Posts: 9,335	New Report: Advances in the Stem Cell Industry: The Future Impact of Innovation LONDON, December 1 /PRNewswire/ -- Global stem cell market sales reached $410 million in 2008, and will grow to $2.68 billion by 2012 according to a new report on http://www.companiesandmarkets.com. Advances in the Stem Cell Industry: The Future Impact Of Innovation, And An Evaluation Of The Commercial Landscape http://www.companiesandmarkets.com/r...CP03OFNH168616 An important milestone in the development of stem cell technology occurred in 2007, when researchers induced human cells into a stem cell state using defined genetic factors. These cells are now known as induced pluripotent stem (IPS) cells; they offer an alternative to using embryonic stem cells. This report takes the implications of IPS cells and other developments into account. Some essential technologies are already in place and stem-cell based therapies have already begun to appear in the marketplace. This has enabled the author to build market estimates based on emerging commercial realities. The stem cell market is already divided into three segments-cell-based treatments, umbilical cord blood banking, and the use of stem cells to evaluate the efficacy and safety of new drugs developed by other methods. Global sales reached $410 million in 2008, and will grow to $2.68 billion by 2012. This growth will reach a projected $5.1 billion in 2014, providing a realistic, and even cautious forecast of the commercial potential of these segments. read... http://twincities.bizjournals.com/tw.../12/01/UKTU027

12-03-2009, 10:14 AM	#3622
manouli Senior Member Join Date: Nov 2004 Location: florida Posts: 9,335	ImmunoCellular Therapeutics Enters into Option Agreement with The University of Texas M. D. Anderson Cancer Center for a Novel Cancer Stem Cell Therapy LOS ANGELES--(BUSINESS WIRE)--Dec 2, 2009 - ImmunoCellular Therapeutics, Ltd. (OTCBB: IMUC) (IMUC), a biotechnology company that is focused on the development of novel immune-based cancer therapies, announced today that it has entered into an option agreement with The University of Texas M. D. Anderson Cancer Center relating to an immunotherapy targeting cancer stem cells (CSCs) which has demonstrated in pre-clinical animal models significant abilities to target and destroy CSCs. This latest agreement bolsters the Company's portfolio of technologies targeting CSCs. This portfolio already features several promising therapies, including ICT-107, a dendritic cell based immunotherapy that recently completed a phase I study, and ICT-121, an off-the-shelf peptide targeting CSCs. more... http://www.medadnews.com/News/Index....ticleid=670522

12-04-2009, 06:46 PM	#3626
manouli Senior Member Join Date: Nov 2004 Location: florida Posts: 9,335	New Technology Captures Tumor Cells from the Bloodstream Category: Laboratory News, Laboratory Pathology Published: December 4 2009 Nano-technology Breakthrough May Prevent Cancers from Metastasizing With the goal of removing tumor cells from the bloodstream, a biomedical engineering team at the University of Arkansas for Medical Sciences (UAMS) in Little Rock has discovered a non-invasive way to identify cancer and to capture tumor cells in the bloodstream. This landmark discovery, could dramatically improve early cancer diagnosis and prevent deadly metastasis. It could also provide a framework for a new type of diagnostic test that could detect metastatic cancer from a blood sample. Led by Vladimir Zharov, Ph.D., D.Sc., Director of the UAMS Phillips Classic Laser and Nanomedicine Laboratory, the scientific team injected a cocktail of golden carbon nanotubes and magnetic nanoparticles with a special biological coating into the bloodstream to target circulating tumor cells. This allows a magnet attached to the skin above peripheral blood vessels to capture tumor cells, especially so-called “rolling cells.” This team published its findings in the Nov. 15, 2009 edition of Nature Nanotechnology. more... http://www.darkdaily.com/new-technol...loodstream-124

12-04-2009, 06:50 PM	#3627
manouli Senior Member Join Date: Nov 2004 Location: florida Posts: 9,335	Public release date: 4-Dec-2009 [ Print \| E-mail \| Share ] [ Close Window ] Contact: Dean Forbes dforbes@fhcrc.org 206-667-2896 Fred Hutchinson Cancer Research Center Cholesterol-lowering drugs also may protect stem cell transplant patients from GVHD SEATTLE – Cholesterol-lowering drugs known as statins are among the most prescribed medicines in the U.S. Now a new study by researchers at Fred Hutchinson Cancer Research Center indicates that statins may protect stem cell transplant patients from one of the most serious complications of the life-saving cancer therapy: graft-versus-host disease, or GVHD. The findings are reported in the Nov. 4 first edition of the journal Blood. In a retrospective study of 567 patients who underwent hematopoietic cell transplantation from matched sibling donors between 2001 and 2007, patients whose donors had been taking statins at the time of stem cell donation experienced no severe acute GVHD. About 15 percent of the stem cell donors in the study were taking statins at the time of transplant. Normally, between 10 percent and 15 percent of transplant patients would be expected to develop severe acute GVHD, according to the study's senior author Marco Mielcarek, M.D., an assistant member of the Hutchinson Center's Clinical Research Division. more.... http://www.eurekalert.org/pub_releas...-cda120409.php

12-04-2009, 06:53 PM	#3628
manouli Senior Member Join Date: Nov 2004 Location: florida Posts: 9,335	Fri Dec 4 07:14:44 2009 Pacific Time Stem Cells Battle for Space BALTIMORE, Dec. 4 (AScribe Newswire) -- The body is a battle zone. Cells constantly compete with one another for space and dominance. Though the manner in which some cells win this competition is well known to be the survival of the fittest, how stem cells duke it out for space and survival is not as clear. A study on fruit flies published in the October 2 issue of Science by Johns Hopkins researchers describes how stem cells win this battle by literally sticking around. "Our work exemplifies how one signal coordinately maintains two types of stem cells in a single niche, or microenvironment," says Erika Matunis, Ph.D., associate professor of cell biology at the Johns Hopkins School of Medicine. "What we found may emerge as common themes of mammalian stem cell niches as they become better characterized." To tackle the stem cell competition quandary, the team looked at fruit fly testes where two different stem cells exist: germline stem cells which give rise to sperm, and somatic stem cells which develop into non-reproductive cell types. more... http://newswire.ascribe.org/cgi-bin/...=2009&public=0

12-05-2009, 12:29 PM	#3629
manouli Senior Member Join Date: Nov 2004 Location: florida Posts: 9,335	Elections have consequences for stem cell research at the University of Michigan December 4, 10:31 PMDetroit Science News ExaminerVince Lamb Two issues decided in last year's general election have resulted in benefits for stem cell research in Michigan, especially at the University of Michigan. First, the election of President Barack Obama, who promised to "restore science to its rightful place" in his Inaugural Address, led to a stimulus package that has so far awarded 342 grants totaling $206.4 million for scientific research at the University of Michigan. Among these awards are thirteen grants totaling $6.8 million from federal stimulus funds for stem cell research. Second, the passage of Proposition 2 in November 2008 allowed the state of Michigan to relax restrictions on embryonic stem cells. While many of the stem-cell projects funded by stimulus money may still have been possible under the pre-2008 state law, they have been made easier under the new constitutional amendment. In a press release, Sean Morrison, director of the U-M Center for Stem Cell Biology, stated that the highly restrictive state laws had discouraged many stem cell researchers from pursuing embryonic stem cell research in the state. "Proposal 2 is going to allow us to hire more people who work in the area of embryonic stem cells, and this NIH grant illustrates that the federal government will provide funding to fuel that expansion," Morrison said. In addition to Morrison, who received a $744,000 stimulus grant from NIH to examine the potential of using human embryonic stem cells to develop a treatment for Hirschsprung disease, a birth defect in which the nervous system that regulates intestinal function does not develop properly, the following researchers receieved stimulus grants to study stem cells. read.... http://www.examiner.com/x-31561-Detr...ty-of-Michigan

12-06-2009, 11:07 AM	#3630
manouli Senior Member Join Date: Nov 2004 Location: florida Posts: 9,335	Multiple Sclerosis Patient Finds Hope Through Stem Cell Treatment -Electromyogram (EMG) findings show improvement in conduction speed and latency -RNL Bio's stem cell therapy demonstrates effective outcomes SEOUL, Korea, Dec. 6 /PRNewswire/ -- RNL Bio Co., Ltd, (www.rnl.co.kr) a leading biopharmaceutical company specialized in adult stem cell therapeutics announced today that a 46-year-old female, Kang Sook Park's Multiple Sclerosis improved tremendously after receiving stem cell treatment. Park was suffering from MS (Multiple Sclerosis), an autoimmune disease that affects the central nervous system (brain and spinal cord). Multiple Sclerosis is a disease in which the nerves of the central nervous system degenerate. MS can cause problems with muscle control and strength, vision, balance, feeling, and thinking. MS is caused by damage to the myelin sheath, the protective covering that surrounds nerve cells. When the myelin sheath is damaged, nerve impulses slow down or stop responding. From the many symptoms of MS, numbness or abnormal sensation in any area is predominant. For the past 20 years, Park suffered from MS. For stem cell injection, she was admitted into Choyang Hospital of Regenerative Medicine in Yanji, China for three weeks. She received stem cells intravenously as well as intrathecally. The injections were given in five intervals -- a total of 1.2 billion cells. more... http://www.prnewswire.com/news-relea...-78625262.html