Stem Cell Articles - Page 210

manouli · 07-30-2008, 10:46 AM

Wednesday, July 30, 2008

U stem cell research may help avoid leg amputation
By: Jed Layton
Issue date: 7/30/08 Section: News
Print

U Health Sciences Center researchers hope a new stem cell study will help patients recover from an intense leg disease, which can lead to amputation if it goes unchecked.

As a professor and chief of vascular surgery at the U School of Medicine, Larry Kraiss is part of a nationwide trial to see if patients' own stem cells will help them recover from a type of peripheral vascular disease.

U medical researchers are searching for five volunteers with a condition called critical limb ischemia-an obstruction of the arteries that feed blood to the legs.

"The hope is that if a stem cell is put into an environment where it recognizes the need for blood vessels, it will form new blood vessels," Kraiss said in a press release.

Kraiss said the disease occurs when plaque builds up in the leg arteries, similar to the way plaque builds up in the heart or brain, causing heart disease and strokes.

"This shuts down the blood supply, causing flesh and tissue to start to die," he said.

more...

http://media.www.dailyutahchronicle....-3395531.shtml

manouli · 07-30-2008, 12:27 PM

Stem cell hope for Scots girl slowly turning into stone
Jul 30 2008

A FAMILY are praying research will save their girl from an incurable disease that is turning her to stone.

Hope Barrie, 11, has a rare condition which is causing her skin to tighten and harden.

Experts say it is like patients are "being turned to stone" as their body produces too much collagen.

The acute form of systemic scleroderma can spread to the organs, leaving Hope, of Tarbolton, Ayrshire, facing a race against time to find a cure.

more...

http://www.dailyrecord.co.uk/lifesty...6908-20676504/

manouli · 07-30-2008, 03:21 PM

Michigan to decide next month on ballot signatures
Associated Press
12:19 PM CDT, July 30, 2008

LANSING, Mich. - Supporters of more embryonic stem cell research and sweeping changes to Michigan government will know within a month whether they collected enough valid voter signatures for the November ballot.

The Board of State Canvassers on Wednesday set an Aug. 21 meeting to get a report from election officials reviewing sample sizes of hundreds of thousands of signatures.

The panel set an Aug. 13 deadline for opponents to challenge sample signatures.

The stem cell measure isn't expected to have opposition over signatures. But opponents likely will challenge signatures for the proposal to cut lawmakers and appellate judges, among other things.

more...

http://www.chicagotribune.com/news/c...C6807869.story

IanTPoulter · 07-31-2008, 03:44 AM

Quote:

Originally Posted by Eric.S

What I find interesting is when people recover sensation. you can't attribute that to PT. you may be able to claim its a mental thing but physical therapy wont recover sensation.

why cant sensation return be attributed to PT? I think you are presuming that PT can only recover use of unrecognised function. Im not so sure that PT in itself does not induce regeneration and or remyelination.
Regarding the statement that we cannot know what return can be attributed to these unethical treatments and what can be attributed to the PT that accompanies these treatments I think logic and reasoning should be used. There are a number of intensive physical therapy centres in the US and elsewhere obtaining far greater results to my knowledge than any of these "stem cell" treatments, there are also a numer of carecure posters undergoing intensive physical therapy that post here on a regular basis and whom also are achieving better results than reported from any of these marketed stem cell treatments. These are facts, so given we are in possession of these facts why on earth would we give the benefit of the doubt to these charlatans marketing these unethical treatments? Seems clear to me.

carbar · 07-31-2008, 05:27 AM

While our scientists struggle with ethics, the Islamic world forges ahead - here is an article from today's Guardian newspaper on research in Iran:

http://www.guardian.co.uk/commentisf...thicsofscience

manouli · 07-31-2008, 09:16 AM

NeoStem Expands Adult Stem Cell Collection Network, Gains Footprint in Key Los Angeles Market and Initiates Waitlist

July 31, 2008: 08:00 AM EST

NEW YORK, July 31 /PRNewswire-FirstCall/ -- NeoStem, Inc. (Amex: NBS) has announced that it has broadened its network of adult stem cell collection centers. Through a development agreement with Stem Collect LLC, NeoStem has added the Hall Center, a vibrant Santa Monica based medical practice.

The Los Angeles area is a significant healthcare market with many academic medical centers and a large concentration of physician practices and hospitals offering a dynamic and diverse population that focuses on healthcare and wellness, as well as new healthcare technologies. To prepare for the demand for collections at the new center, clients are being offered the opportunity to join a waitlist by contacting NeoStem at 1-888-STEM BANK to hold a priority position for an appointment once the center is open. It is expected that the center will open in August.

more...

http://money.cnn.com/news/newsfeeds/...___NYTH017.htm

manouli · 07-31-2008, 09:13 PM

Stem-cell advance for motor neurone disease

By Steve Connor, Science Editor
Friday, 1 August 2008

Scientists have succeeded in transforming skin cells from two sisters with motor neurone disease into the same kind of nerve cells being destroyed by their illness, raising the possibility that the new cells can be transplanted back into them to offset the degenerative condition.

In a major breakthrough, the skin cells of the two women, aged 82 and 89, were turned into mature nerve cells. The achievement promises to revolutionise the understanding and treatment of a range of incurable illnesses.

The skin cells were genetically altered by a laboratory technique that "reprogrammed" them back to their original embryonic state, before being grown into the specialised motor neurons that carry signals from brain to muscles.

Scientists hope that the creation of adult nerve cells from the skin of patients with motor neurone disease – which cripples muscles – will result in a better understanding of how things go wrong, as well as leading to a new approach to testing drugs and therapies that could lead to better treatments, or possibly a cure.

"No one has ever managed to isolate these neurons from a patient and grow them in a dish," said Professor Kevin Eggan, of Harvard University in Cambridge, Massachusetts, who led the study, published in the journal Science. "Now we can make limitless supplies of the cells that die in this awful disease. This will allow us to study these neurons in a lab dish and figure out what's happening."

more...

http://www.independent.co.uk/news/sc...se-882606.html

manouli · 07-31-2008, 09:17 PM

Scientists Achieve Stem-Cell Milestone
Thursday, Jul. 31, 2008 By ALICE PARK

After nearly a decade of setbacks and false starts, stem-cell science finally seems to be hitting its stride. Just a year after Japanese scientists first reported that they had generated stem cells by reprogramming adult skin cells — without using embryos — American researchers have managed to use that groundbreaking technique to achieve another scientific milestone. They created the first nerve cells from reprogrammed stem cells — an important demonstration of the potential power of stem-cell-based treatments to cure disease.

more...

http://www.time.com/time/health/arti...,00.html?imw=Y

manouli · 07-31-2008, 09:21 PM

Hope you read this Agios, be well.

Scientists Make Stem Cells From ALS Patient
by Joe Palca

Listen Now [3 min 52 sec] add to playlist

All Things Considered, July 31, 2008 · ALS is a disease of the nervous system. Over time, a special kind of nerve cell called a motor neuron dies, leaving the patient unable to move.

"These nerve cells which die have been impossible to culture in the laboratory, and as a result we have no idea why they die," says Kevin Eggan, a stem cell biologist at the Harvard Stem Cell Institute.

Eggan says one way to get a patient's nerve cells to grow in the lab is to start by making embryonic stem cells from that patient. Embryonic stem cells are pluripotent: They can turn into any cell in the body. So, in theory, you could use them to make nerve cells.

Making embryonic stem cells from adult humans hasn't been possible, however. Not only are there technical hurdles that haven't been overcome, but some people oppose the very idea for moral reasons.

more...

http://www.npr.org/templates/story/s...oryId=93143775

manouli · 07-31-2008, 09:29 PM

Personalized Stem Cells One Step Closer to Reality
Researchers Create Disease-Specific, Individualized Human Stem Cells
By RADHA CHITALE
ABC News Medical Unit
July 31, 2008

For the first time, scientists have proven that embryonic-like stem cells that are specific to both a person and to a disease can be manufactured using adult human cells.

Personalized stem cells may be the holy grail of science because of their potential to treat and allow the study of a myriad of diseases and conditions. And while there are still a number of hurdles to clear before this advance can be applied to humans, in the clinical setting this latest step, some say, shows promise of eventual human therapies.

Researchers from Harvard and Columbia Universities used skin cells from two patients with Amyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig's disease, to create stem cells and then reprogrammed them to morph into replacement motor neurons.

"It opens doors to making patient-specific stem cell lines," said Dr. Kevin Eggan, principle faculty member at the Harvard Stem Cell Institute and lead author of a study that was released today in the journal Science. "You can use these cells to make the actual cell type for that person's disease."

more....

http://abcnews.go.com/Health/story?id=5489479&page=1

07-31-2008, 05:27 AM	#2095
carbar Senior Member Join Date: Dec 2004 Location: France Posts: 2,438	Stem cell research in Iran - a British scientist's view While our scientists struggle with ethics, the Islamic world forges ahead - here is an article from today's Guardian newspaper on research in Iran: http://www.guardian.co.uk/commentisf...thicsofscience __________________ Think Tall! www.stepnow.org http://www.irishstemcellfoundation.org

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07-30-2008, 10:46 AM	#2091
manouli Senior Member Join Date: Nov 2004 Location: florida Posts: 9,339	Wednesday, July 30, 2008 U stem cell research may help avoid leg amputation By: Jed Layton Issue date: 7/30/08 Section: News Print U Health Sciences Center researchers hope a new stem cell study will help patients recover from an intense leg disease, which can lead to amputation if it goes unchecked. As a professor and chief of vascular surgery at the U School of Medicine, Larry Kraiss is part of a nationwide trial to see if patients' own stem cells will help them recover from a type of peripheral vascular disease. U medical researchers are searching for five volunteers with a condition called critical limb ischemia-an obstruction of the arteries that feed blood to the legs. "The hope is that if a stem cell is put into an environment where it recognizes the need for blood vessels, it will form new blood vessels," Kraiss said in a press release. Kraiss said the disease occurs when plaque builds up in the leg arteries, similar to the way plaque builds up in the heart or brain, causing heart disease and strokes. "This shuts down the blood supply, causing flesh and tissue to start to die," he said. more... http://media.www.dailyutahchronicle....-3395531.shtml

07-30-2008, 12:27 PM	#2092
manouli Senior Member Join Date: Nov 2004 Location: florida Posts: 9,339	Stem cell hope for Scots girl slowly turning into stone Jul 30 2008 A FAMILY are praying research will save their girl from an incurable disease that is turning her to stone. Hope Barrie, 11, has a rare condition which is causing her skin to tighten and harden. Experts say it is like patients are "being turned to stone" as their body produces too much collagen. The acute form of systemic scleroderma can spread to the organs, leaving Hope, of Tarbolton, Ayrshire, facing a race against time to find a cure. more... http://www.dailyrecord.co.uk/lifesty...6908-20676504/

07-30-2008, 03:21 PM	#2093
manouli Senior Member Join Date: Nov 2004 Location: florida Posts: 9,339	Michigan to decide next month on ballot signatures Associated Press 12:19 PM CDT, July 30, 2008 LANSING, Mich. - Supporters of more embryonic stem cell research and sweeping changes to Michigan government will know within a month whether they collected enough valid voter signatures for the November ballot. The Board of State Canvassers on Wednesday set an Aug. 21 meeting to get a report from election officials reviewing sample sizes of hundreds of thousands of signatures. The panel set an Aug. 13 deadline for opponents to challenge sample signatures. The stem cell measure isn't expected to have opposition over signatures. But opponents likely will challenge signatures for the proposal to cut lawmakers and appellate judges, among other things. more... http://www.chicagotribune.com/news/c...C6807869.story

07-31-2008, 09:16 AM	#2096
manouli Senior Member Join Date: Nov 2004 Location: florida Posts: 9,339	NeoStem Expands Adult Stem Cell Collection Network, Gains Footprint in Key Los Angeles Market and Initiates Waitlist July 31, 2008: 08:00 AM EST NEW YORK, July 31 /PRNewswire-FirstCall/ -- NeoStem, Inc. (Amex: NBS) has announced that it has broadened its network of adult stem cell collection centers. Through a development agreement with Stem Collect LLC, NeoStem has added the Hall Center, a vibrant Santa Monica based medical practice. The Los Angeles area is a significant healthcare market with many academic medical centers and a large concentration of physician practices and hospitals offering a dynamic and diverse population that focuses on healthcare and wellness, as well as new healthcare technologies. To prepare for the demand for collections at the new center, clients are being offered the opportunity to join a waitlist by contacting NeoStem at 1-888-STEM BANK to hold a priority position for an appointment once the center is open. It is expected that the center will open in August. more... http://money.cnn.com/news/newsfeeds/...___NYTH017.htm

07-31-2008, 09:13 PM	#2097
manouli Senior Member Join Date: Nov 2004 Location: florida Posts: 9,339	Stem-cell advance for motor neurone disease By Steve Connor, Science Editor Friday, 1 August 2008 Scientists have succeeded in transforming skin cells from two sisters with motor neurone disease into the same kind of nerve cells being destroyed by their illness, raising the possibility that the new cells can be transplanted back into them to offset the degenerative condition. In a major breakthrough, the skin cells of the two women, aged 82 and 89, were turned into mature nerve cells. The achievement promises to revolutionise the understanding and treatment of a range of incurable illnesses. The skin cells were genetically altered by a laboratory technique that "reprogrammed" them back to their original embryonic state, before being grown into the specialised motor neurons that carry signals from brain to muscles. Scientists hope that the creation of adult nerve cells from the skin of patients with motor neurone disease – which cripples muscles – will result in a better understanding of how things go wrong, as well as leading to a new approach to testing drugs and therapies that could lead to better treatments, or possibly a cure. "No one has ever managed to isolate these neurons from a patient and grow them in a dish," said Professor Kevin Eggan, of Harvard University in Cambridge, Massachusetts, who led the study, published in the journal Science. "Now we can make limitless supplies of the cells that die in this awful disease. This will allow us to study these neurons in a lab dish and figure out what's happening." more... http://www.independent.co.uk/news/sc...se-882606.html

07-31-2008, 09:17 PM	#2098
manouli Senior Member Join Date: Nov 2004 Location: florida Posts: 9,339	Scientists Achieve Stem-Cell Milestone Thursday, Jul. 31, 2008 By ALICE PARK After nearly a decade of setbacks and false starts, stem-cell science finally seems to be hitting its stride. Just a year after Japanese scientists first reported that they had generated stem cells by reprogramming adult skin cells — without using embryos — American researchers have managed to use that groundbreaking technique to achieve another scientific milestone. They created the first nerve cells from reprogrammed stem cells — an important demonstration of the potential power of stem-cell-based treatments to cure disease. more... http://www.time.com/time/health/arti...,00.html?imw=Y

07-31-2008, 09:21 PM	#2099
manouli Senior Member Join Date: Nov 2004 Location: florida Posts: 9,339	Hope you read this Agios, be well. Scientists Make Stem Cells From ALS Patient by Joe Palca Listen Now [3 min 52 sec] add to playlist All Things Considered, July 31, 2008 · ALS is a disease of the nervous system. Over time, a special kind of nerve cell called a motor neuron dies, leaving the patient unable to move. "These nerve cells which die have been impossible to culture in the laboratory, and as a result we have no idea why they die," says Kevin Eggan, a stem cell biologist at the Harvard Stem Cell Institute. Eggan says one way to get a patient's nerve cells to grow in the lab is to start by making embryonic stem cells from that patient. Embryonic stem cells are pluripotent: They can turn into any cell in the body. So, in theory, you could use them to make nerve cells. Making embryonic stem cells from adult humans hasn't been possible, however. Not only are there technical hurdles that haven't been overcome, but some people oppose the very idea for moral reasons. more... http://www.npr.org/templates/story/s...oryId=93143775

07-31-2008, 09:29 PM	#2100
manouli Senior Member Join Date: Nov 2004 Location: florida Posts: 9,339	Personalized Stem Cells One Step Closer to Reality Researchers Create Disease-Specific, Individualized Human Stem Cells By RADHA CHITALE ABC News Medical Unit July 31, 2008 For the first time, scientists have proven that embryonic-like stem cells that are specific to both a person and to a disease can be manufactured using adult human cells. Personalized stem cells may be the holy grail of science because of their potential to treat and allow the study of a myriad of diseases and conditions. And while there are still a number of hurdles to clear before this advance can be applied to humans, in the clinical setting this latest step, some say, shows promise of eventual human therapies. Researchers from Harvard and Columbia Universities used skin cells from two patients with Amyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig's disease, to create stem cells and then reprogrammed them to morph into replacement motor neurons. "It opens doors to making patient-specific stem cell lines," said Dr. Kevin Eggan, principle faculty member at the Harvard Stem Cell Institute and lead author of a study that was released today in the journal Science. "You can use these cells to make the actual cell type for that person's disease." more.... http://abcnews.go.com/Health/story?id=5489479&page=1