Doctors rapidly matured eggs from prepubescent girls.

[Wise Young]

I am not sure that I agree with the tongue-in-cheek extrapolation of the findings to fanciful speculations about "instant grandchild". What this does mean is that girls that have cancer and ovarietomy can now save their eggs. It also means that there will be thousands of eggs that could be used for creating embryonic stem cells.

Wise.

http://www.slate.com/id/2169583/

They extracted immature eggs from 16 girls, including seven eggs from a 5-year old, 8 from an 8-year-old, and 17 from a 10-year-old. The eggs "were then matured in a Petri dish over one to two days until they resembled those of a 20-year-old woman." The procedure "achieved full maturation in 41" of 130 eggs. The eggs were then frozen; it's not yet known whether they'll be viable when thawed. All the girls had cancer. Official rationale: Now girls who survive cancer and chemo can have babies when they're ready. Off-label use No. 1: Now parents of any girl can have some of her eggs extracted, rapidly matured, and frozen just in case she later becomes infertile. Off-label use No. 2: Instant solution to the shortage of human eggs for research. Off-label use No. 3: Instant grandchild to replace your cancer-stricken daughter.

[manouli]

Originally Posted by Wise Young

I am not sure that I agree with the tongue-in-cheek extrapolation of the findings to fanciful speculations about "instant grandchild". What this does mean is that girls that have cancer and ovarietomy can now save their eggs. It also means that there will be thousands of eggs that could be used for creating embryonic stem cells.

Wise.

http://www.slate.com/id/2169583/

Dr. Young I saw this morning this one with adults:

Freeze, thaw and fertilise: Breakthrough seen for infertile women

The first baby to be created from an egg matured in a laboratory, frozen, thawed and then fertilised, has been born in Canada, researchers told a medical conference on Monday.

The baby girl was born to a woman diagnosed with advanced ovarian disease, and three other women in the 20-person trial group are pregnant by the same technique, researchers said.

Doctors already collect and store eggs from women who face cancer treatment that could cause sterility.

The eggs -- harvested after stimulating the ovaries with hormones -- are fertilised in-vitro with their partner's sperm, then frozen. After the cancer therapy, the eggs are then thawed and implanted.


The Canadian team said the prototype technique took this fertility preservation a major step further. The eggs were recovered from unstimulated ovaries and in addition were fertilised after they had been frozen and then thawed, and not before.

"Until now, it was not known whether oocytes [human eggs] collected from unstimulated ovaries, matured in vitro and then vitrified could survive thawing, be fertilised successfully and result in a viable pregnancy after embryo transfer," said Hananel Holzer, who led the team from the McGill Reproductive Center in Montreal.

"We have demonstrated for the first time that it is possible to do this and, so far, we have achieved four successful pregnancies, one of which has resulted in a live birth. The other three pregnancies are ongoing."

The breakthrough was announced at the annual conference of the European Society of Human Reproduction and Embryology (EHSRE), meeting in this southeastern French city.

The trial group comprised 20 women, whose average age was about 30, who had been diagnosed by ultrasound to have polycystic ovarian syndrome (PCOS), a fertility-threatening hormonal disorder that affects around 10 percent of all women of child-bearing years.

more:

http://www.physorg.com/news102576984.html