|03-16-2006, 03:24 AM||#1|
Join Date: Jul 2001
Location: New Brunswick, NJ, USA
Cygenics Biotech Awarded Cell Culture Spinner Flask Patent
I normally would not post a patent announcement of a technology advance of this type. However, after coming back from the Stem Cell Meeting in San Francisco, this particular announcement struck a bell for me. There is a need for significant investment into cell growing technologies because our current methods are limiting our ability to go rapidly from laboratory to clinical trials.
One of the main obstacles to producing cells for clinical application is the large volume of cells required. Before cells can go to clinical trial or be used in large numbers of people, methods must be developed to grow billions of cells. In many studies of rats and mice, the transplantation procedures use only millions of cells at the most. In humans, it may be necessary to use billions. To treat millions of people, therefore, one will need scale up the cell production by a million times or more.
Most cell production systems are expensive and cumbersome. This particular innovation is of interest because it is a 500 ml system that can produce similar results as a 5 liter system. This and other technologies may be key to generating the large numbers of customized cells for clinical trials. Little technical advances like these may make the difference between success and failure of clinical trials, as well as lower the cost and increase the rate of clinical trials of cell transplantation therapies.
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