Chen, et al. (2004). Longitudinal myelitis in systemic lupus erythematosus

Wise Young · 03-30-2004, 05:09 PM

• Chen HC, Lai JH, Juan CJ, Kuo SY, Chen CH and Chang DM (2004). Longitudinal myelitis as an initial manifestation of systemic lupus erythematosus. Am J Med Sci. 327: 105-8. Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, ROC. Transverse myelitis is a rare and serious complication of systemic lupus erythematosus (SLE). A longitudinal involvement of the spinal cord with lupus-related transverse myelitis is more unusual. Only 7 cases have been reported. We describe a 53-year-old woman presenting with short-term paraplegia as an initial manifestation of SLE with longitudinal myelitis. She had a partial response to treatment with pulse cyclophosphamide and high-dose corticosteroids after follow-up more than 2 years. To the best of our knowledge, this is the first case report of "longitudinal" myelitis as an initial presentation of SLE. Magnetic resonance imaging typically shows increased signal intensity in T2-weighted images, cord swelling, and contrast enhancement over several spinal segments. The possibility of SLE should be kept in mind in women presenting with paraplegia with no apparent cause.

Lourdes · 04-05-2005, 03:45 AM

Dear Mr Young,
I'm writing to you from Spain, and my boyfriend has been diagnosed longitudinal myelitis. He is now 29, but this started one year ago. The origin is unknown and he's been treated with steroids to minimize the inflammation. However it's gone very slowly an has left me tetraplegic and needs respiratory help. Could you please tell me where I can find more information on cases like this?
Thanks a lot,
Lourdes

03-30-2004, 05:09 PM	#1
Wise Young Administrator Join Date: Jul 2001 Location: New Brunswick, NJ, USA Posts: 37,975	Chen, et al. (2004). Longitudinal myelitis in systemic lupus erythematosus • Chen HC, Lai JH, Juan CJ, Kuo SY, Chen CH and Chang DM (2004). Longitudinal myelitis as an initial manifestation of systemic lupus erythematosus. Am J Med Sci. 327: 105-8. Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, ROC. Transverse myelitis is a rare and serious complication of systemic lupus erythematosus (SLE). A longitudinal involvement of the spinal cord with lupus-related transverse myelitis is more unusual. Only 7 cases have been reported. We describe a 53-year-old woman presenting with short-term paraplegia as an initial manifestation of SLE with longitudinal myelitis. She had a partial response to treatment with pulse cyclophosphamide and high-dose corticosteroids after follow-up more than 2 years. To the best of our knowledge, this is the first case report of "longitudinal" myelitis as an initial presentation of SLE. Magnetic resonance imaging typically shows increased signal intensity in T2-weighted images, cord swelling, and contrast enhancement over several spinal segments. The possibility of SLE should be kept in mind in women presenting with paraplegia with no apparent cause.

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04-05-2005, 03:45 AM	#2
Lourdes Junior Member Join Date: Apr 2005 Location: Lorca, Murcia, Spain Posts: 1	Dear Mr Young, I'm writing to you from Spain, and my boyfriend has been diagnosed longitudinal myelitis. He is now 29, but this started one year ago. The origin is unknown and he's been treated with steroids to minimize the inflammation. However it's gone very slowly an has left me tetraplegic and needs respiratory help. Could you please tell me where I can find more information on cases like this? Thanks a lot, Lourdes