Miami Project announcement, 10 AM Today (Tuesday)

[micah_d]

Originally Posted by NoDecafPlz

What are talking about? We're all team Wise here, or most of us at least.

Who do you perceive e-pissing on Wise?

Miami project has not shown enough return on investment. I am not the only one that feels that way.

what specific changes do you feel MP should make to get faster results?

[rjg]

Originally Posted by NoDecafPlz

What are talking about? We're all team Wise here, or most of us at least.

Who do you perceive e-pissing on Wise?

Miami project has not shown enough return on investment. I am not the only one that feels that way.

Most of us are on Wise's side. But there are a few. No need to name names, as I'm too classy for such behavior. Paolo. Grammy. Christopher Paddington. Jerry Silver.

[rjg]

Originally Posted by micah_d

what specific changes do you feel MP should make to get faster results?

I know you didn't ask me, but here's a suggestion: fund more than one human trial every 25 years. 2 human trials every quarter century would double the odds that the Miami Project's millions will lead to something worthwhile.

[ineedmyelin]

Originally Posted by rjg

Most of us are on Wise's side. But there are a few. No need to name names, as I'm too classy for such behavior. Paolo. Grammy. Christopher Paddington. Jerry Silver.

true dat!

[rjames]

Originally Posted by rjg

I know you didn't ask me, but here's a suggestion: fund more than one human trial every 25 years. 2 human trials every quarter century would double the odds that the Miami Project's millions will lead to something worthwhile.

That's a good one!!!

[lynnifer]

Originally Posted by rjg

Most of us are on Wise's side. But there are a few. No need to name names, as I'm too classy for such behavior. Paolo. Grammy. Christopher Paddington. Jerry Silver.

I don't think that's true or appropriate in this thread, but it's obvious you are more than likely welcome to your opinion.

DA was famous for challenging Wise. I miss him a lot. I appreciate we have more who don't accept blindly, but challenge as well. That's the crux of science isn't it? Dont' forget kivi!

[BSgimp]

I dont understand people on this forum. Unreasonable behavior seems to be a common place here. I ask why are you looking to argue? What is the point? You are not contributing to discussion with knowledge but with pointless bickering.

We have the theory here.. based on years of research and studies. We need to understand what it would imply, and then compare the theory to the experiment and experience. This of course being the trial. We compare it directly with the observation to see if it works. If it disagrees with the experiment its wrong. In that simple statement is the key to science. Now, it does not matter who came up with theory or who did the experiment. It can be Wise, Silver or G.W.Bush for that matter. What is important is the result and this is what we need to focus on. Nobody can know for sure what the result of experiments will be .. even the person behind the theory. Picking sides like children is pointless waste of time and energy. Lets focus on science itself. Questioning is also important part of science and extraordinary claims require extraordinary evidence. This is why we wont get any info from a scientist before the claim can be verified by experiment.

Now, the OP came with amazing news. New trial means we can verify if this therapy works. Even if it does not it mean we can scratch it of the list and learn from it.

[dan_nc]

From the FAQ about the study,
http://www.themiamiproject.org/page.aspx?pid=1047

Is this a first step in the cure for paralysis?
No - this is a Phase 1 safety study.

So there you have it. In their own words, this is not the first step in the cure for paralysis.

[Fly_Pelican_Fly]

As I understand it MP have leveraged lessons learned from the abandoned Geron study, including the device used for administering their hESC cells. To complete a safety study with any cell type being injected into the spinal cord under US FDA regulations would be a significant milestone. Many other organisations see this as a crucial step.

Do I think Schwann cells will cure chronic SCI? No. Do MP think that Schwann cells will cure chronic SCI - I hope not otherwise I will seriously doubt their credibility as a research group. I think and hope that this is just a first step towards realising a combinatory approach later with a number of other lines of science (namely Ch'ase). And if not, then we go after them

As for their spending to date - well, that is another story. Put it this way, they are further ahead than Rick Hansen and CDRF in terms of getting a trial going in North America. They are not my favourite organisation, but there is no point bashing them now they have stuck their neck out and started a trial. That would be destructive.

One thing that MP can shout about is that they can run the trial within their big shiny facilities without worrying about other centres.

[swh2007]

Originally Posted by Fly_Pelican_Fly

As I understand it MP have leveraged lessons learned from the abandoned Geron study, including the device used for administering their hESC cells. To complete a safety study with any cell type being injected into the spinal cord under US FDA regulations would be a significant milestone. Many other organisations see this as a crucial step.

Do I think Schwann cells will cure chronic SCI? No. Do MP think that Schwann cells will cure chronic SCI - I hope not otherwise I will seriously doubt their credibility as a research group. I think and hope that this is just a first step towards realising a combinatory approach later with a number of other lines of science (namely Ch'ase). And if not, then we go after them

As for their spending to date - well, that is another story. Put it this way, they are further ahead than Rick Hansen and CDRF in terms of getting a trial going in North America. They are not my favourite organisation, but there is no point bashing them now they have stuck their neck out and started a trial. That would be destructive.

One thing that MP can shout about is that they can run the trial within their big shiny facilities without worrying about other centres.

Their so called big shiny facility is just another medium (at best) sized medical building in a huge sea of medical buildings at the University of Miami Hospital. It does not seem big at all when you tour it. I am a big Dr Young supporter but I appreciate whoever is trying to find a cure. Just a comment about something I see as a misconception.