Nerve Grafting for Spinal Cord Injury in Cats: Are We Close to Translational Research

jadedsimiles · 03-14-2011, 02:10 AM

Nerve Grafting for Spinal Cord Injury in Cats: Are We Close to Translational Research?
Hanna, Amgad S; Côté, Marie-Pascale; Houlé, John; Dempsey, Robert

http://journals.lww.com/neurosurgery...ts__Are.1.aspx

Neurosurgery:
April 2011 - Volume 68 - Issue 4 - pp N14-N15
doi: 10.1227/01.neu.0000395789.12519.fc
Science Times

As you can see... There is little to no information given, but the title is really irking my patience. I hope they publish it soon, I am giving a presentation on SCI's in class and I was hoping I could discuss other treatments.

From the little summary I got from Columbia University's site, it seems like a very treacherous treatment, however perhaps it could work. What are your thoughts on nerve grafting?

-Hannah

wildwilly · 03-14-2011, 08:41 AM

Here is a link to a related article (2010).

http://www.ncbi.nlm.nih.gov/pubmed/20599980

litespeed4 · 03-14-2011, 09:11 AM

Basically they performed a nerve graft from C7 to T1 using ChABC to suppress CSPG. There was evidence of axon growth into and out of the graft into the spinal cord but...

Quote:

The severity of injury was not sufficient to study clinical improvement.

Quote:

The efficacy of treatments in large animal models will best provide preclinical evidence that is necessary before moving forward with human SCI trials

FYI The article sites the following
Cote MP, Hanna A, Lemay MA, et al. Peripheral nerve grafts after cervical spinal cord injury in adult cats. Exp Neurol. 2010;225(1):173-182.

03-14-2011, 02:10 AM	#1
jadedsimiles Junior Member Join Date: Mar 2011 Location: Manhattan Posts: 5	Nerve Grafting for Spinal Cord Injury in Cats: Are We Close to Translational Research Nerve Grafting for Spinal Cord Injury in Cats: Are We Close to Translational Research? Hanna, Amgad S; Côté, Marie-Pascale; Houlé, John; Dempsey, Robert http://journals.lww.com/neurosurgery...ts__Are.1.aspx Neurosurgery: April 2011 - Volume 68 - Issue 4 - pp N14-N15 doi: 10.1227/01.neu.0000395789.12519.fc Science Times As you can see... There is little to no information given, but the title is really irking my patience. I hope they publish it soon, I am giving a presentation on SCI's in class and I was hoping I could discuss other treatments. From the little summary I got from Columbia University's site, it seems like a very treacherous treatment, however perhaps it could work. What are your thoughts on nerve grafting? -Hannah

03-14-2011, 08:41 AM	#2
wildwilly Moderator Join Date: Sep 2004 Location: Michigan Posts: 1,775	Here is a link to a related article (2010). http://www.ncbi.nlm.nih.gov/pubmed/20599980 __________________ “As the cast of villains in SCI is vast and collaborative, so too must be the chorus of hero's that rise to meet them” Ramer et al 2005

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