Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi. 2008 Mar;22(1):60-2.

[Acute transverse myelitis associated with Coxsackievirus B- A retrospective analysis of 7 patients.][Article in Chinese]

Liu ZD, Wang DX, Feng ZJ.
Department of Neurology, Beijing Friendship Hospital Affiliated to Capital Medical University, Beijing 100050 China.

OBJECTIVE: Acute Transverse myelitis (ATM) is a focal inflammatory disorder of the spinal cord, resulting in motor, sensory, and autonomic nerve dysfunction. There is often a clearly defined rostral border of sensory dysfunction. Nowadays, the pathogenesis of ATM is not clear. The present study aimed to understand possible relationship between ATM and infection with Coxsackievirus B. METHODS: IgM antibody against Coxsackievirus B was detected in cerebrospinal fluid of 33 patients with ATM. RESULTS: In 7 of the 33 cases with ATM, the IgM andtibody Coxsackievirus B (CVB) was positive. No infections with other pathogens were found at the onset of the disease. CONCLUSION: The pathogenesis of ATM may involve infection with Coxsackievirus B. [Key words] Myelitis, transverse; Coxsackievirus infections.