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Thread: Cranberries for preventing urinary tract infections

  1. #1
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    Cranberries for preventing urinary tract infections

    http://www.mrw.interscience.wiley.co...321/frame.html

    Cranberries for preventing urinary tract infections

    Jepson RG, Craig JC. Cranberries for preventing urinary tract infections. Cochrane Database of Systematic Reviews 2008, Issue 1

    Abstract

    Background
    Cranberries have been used widely for several decades for the prevention and treatment of urinary tract infections (UTIs).

    Objectives
    To assess the effectiveness of cranberry products in preventing UTIs in susceptible populations.

    Search strategy
    We searched MEDLINE, EMBASE, the Cochrane Central Register of Controlled Trials (CENTRAL in The Cochrane Library) and the Internet. We contacted companies involved with the promotion and distribution of cranberry preparations and checked reference lists of review articles and relevant studies.
    Date of last search: January 2007.

    Selection criteria
    All randomised controlled trials (RCTs) or quasi-RCTs of cranberry products for the prevention of UTIs in all populations.

    Data collection and analysis
    Two authors independently assessed and extracted information. Information was collected on methods, participants, interventions and outcomes (UTIs - symptomatic and asymptomatic, side effects, adherence to therapy). Relative risk (RR) were calculated where appropriate, otherwise a narrative synthesis was undertaken. Quality was assessed using the Cochrane criteria.

    Main results
    Ten studies (n = 1049, five cross-over, five parallel group) were included. Cranberry/cranberry-lingonberry juice versus placebo, juice or water was evaluated in seven studies, and cranberries tablets versus placebo in four studies (one study evaluated both juice and tablets). Cranberry products significantly reduced the incidence of UTIs at 12 months (RR 0.65, 95% CI 0.46 to 0.90) compared with placebo/control. Cranberry products were more effective reducing the incidence of UTIs in women with recurrent UTIs, than elderly men and women or people requiring catheterisation. Six studies were not included in the meta-analyses due to methodological issues or lack of available data. However, only one reported a significant result for the outcome of symptomatic UTIs. Side effects were common in all studies, and dropouts/withdrawals in several of the studies were high.

    Authors' conclusions
    There is some evidence that cranberry juice may decrease the number of symptomatic UTIs over a 12 month period, particularly for women with recurrent UTIs. It's effectiveness for other groups is less certain. The large number of dropouts/withdrawals indicates that cranberry juice may not be acceptable over long periods of time. It is not clear what is the optimum dosage or method of administration (e.g. juice, tablets or capsules). Further properly designed studies with relevant outcomes are needed.

    Plain language summary
    Cranberries for preventing urinary tract infections

    Cranberries (usually as cranberry juice) have been used to try and prevent urinary tract infections (UTIs). Cranberries contain a substance that can prevent bacteria from sticking on the walls of the bladder. This may help prevent bladder and other urinary tract infections. This review identified 10 studies (1049 participants) comparing cranberry products with placebo, juice or water. There was some evidence to show that cranberries (juice and capsules) can prevent recurrent infections in women. However, the evidence for elderly men and women was less clear, and there is evidence that is not effective in people who need catheterisation. Many people in the trials stopped drinking the juice, suggesting it may not be a popular intervention. In addition it is not clear how long cranberry juice needs to be taken to be effective or what the required dose might be.

  2. #2
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    Leif, not exactely NEWS Cranberry. Belongs in Food or...?
    "The world will not perish for want of wonders but for want of wonder."
    J.B.S.Haldane

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    I know its not news, just another study. Read it or skip it.

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    Quote Originally Posted by Leif
    I know its not news, just another study. Read it or skip it.
    Fine! Why Life?
    "The world will not perish for want of wonders but for want of wonder."
    J.B.S.Haldane

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    Life Questions and answers for life

    Why not, what do you suggest, Politics?

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    Quote Originally Posted by Leif
    Why not, what do you suggest, Politics?
    Hello! Using that rationale, EVERYTING should be posted to Life. We have subcatagory (to Life) topic forums for things specifically concerning the subcatagory; like Food, where, strangely, I got the OTHER cranberry topic post.
    "The world will not perish for want of wonders but for want of wonder."
    J.B.S.Haldane

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    So what is you’re suggestion then, it doesn’t help much to jump up and down.

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    Quote Originally Posted by Leif
    So what is you’re suggestion then, it doesn’t help much to jump up and down.


    I already mentioned the Food forum (doh, cranberries are a FOOD). Do you need a diagram or a pie-chart to help you out here?
    "The world will not perish for want of wonders but for want of wonder."
    J.B.S.Haldane

  9. #9
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    Yes you mentioned “Food” and you said “like Food” in the above long sentence of yours here. I didn’t take that as a suggestion to my specific subject thread but more towards you was thinking of food. Are you suggesting that it should be moved to “Food” – yes or no? A lot of things are also food, like a lot of things as you said could fit in life.

  10. #10
    The jury seems forever out on cranberries and UTI's. I take a megadose when travelling or if I feel one coming on, whether it makes a difference or not I don't know.

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