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Thread: Jefferson Urologists Studying Tissue-Engineered Bladders to Help Spinal Cord Injury P

  1. #1

    Jefferson Urologists Studying Tissue-Engineered Bladders to Help Spinal Cord Injury P

    I didn't realize they were at this point but this is really encouraging.

    http://www.tengion.com/library/press_20070917.cfm

    http://clinicaltrial.gov/ct/show/NCT...712135?order=2

  2. #2
    Senior Member
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    litespeed4,
    I think someone in this community is particpating in this study. I thought I saw under the clinical trials forum.

  3. #3

    New Procedure Could Improve Bladders in Spinal Cord Patients

    this sounds good. I'll try to get more information, anyone here knows more?


    New Procedure Could Improve Bladders in Spinal Cord Patients



    by KYW's Lynne Adkins

    Urologists at Thomas Jefferson University Hospital are studying a procedure that could improve the bladder control of adults with spinal cord injuries.

    People with spinal cord injuries often have malfunctioning bladders.

    Assistant professor of urology Dr. Patrick Shenot says this procedure would give the patient some help from a bladder grown from their own cells.



    more:

    http://www.kyw1060.com/pages/1031742...ntentId=989503

  4. #4
    Senior Member Bhaskar's Avatar
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    Neo-bladder for paralysis in trials

    Jefferson Urologists Studying Regenerated Neo-Bladder to Help Spinal Cord Injury Patients

    Urologists at Thomas Jefferson University Hospital are studying whether a neo-bladder construct grown from a patient's own cells can improve bladder function for adult spinal cord injury patients.

    Jefferson is only one of six sites in the U.S. enrolling participants in this clinical trial for the lab-grown neo-bladder construct that will involve a total of 10 patients.

    "It's never been done in adults before," said primary investigator Patrick Shenot, M.D., instructor in Urology, Jefferson Medical College of Thomas Jefferson University, noting that a similar study is being conducted with children with spina bifida.

    The neo-bladder constructs are being developed by Tengion, Inc. in their pilot manufacturing facility.

    Each neo-bladder construct consists of a biodegradable scaffold seeded with urothelial and smooth muscle cells cultured in Tengion's facility from the patient's own bladder cells.

    To participate in the study, a patient must be 18 to 65 years of age, have had a spinal cord injury for more than a year and diagnosed with a neurogenic bladder that is not adequately responding to medical therapy.

    The urologist first performs a biopsy on the patient to retrieve the cells. The cells are then sent to Tengion's manufacturing facility where they are grown in culture and then seeded onto a biodegradable scaffold in the shape of a bladder.

    More : http://www.jefferson.edu/news/index....icle15203.html

  5. #5
    Hi

    CC member mlkost is part of this study, and posted about it 1 yr post surgery. Do a search for tengion or mlkost if you are interested
    "The impossible is just that which hasn't been done yet.Impossible is nothing"

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