Thread: Stem Cell Articles

  1. #1321
    Senior Member Leo's Avatar
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    from the article,

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    Our HuCNS-SC cells are already in clinical testing for the brain, and we have announced plans to initiate a clinical trial for spinal cord injury later this year. This collaboration advances our mission to develop novel treatments for diseases of all three elements of the central nervous system – the brain, the spinal cord and the eye.”

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    Quote Originally Posted by Bhaskar
    StemCells Employs Casey Eye Institute to Test Neural Stem Cell Product for Treating Retinal Degeneration

    StemCells will work with the Oregon Health & Science University Casey Eye Institute to evaluate its purified human neural stem cell candidate, HuCNS-SC®, as a treatment for retinal degeneration.

    The parties will investigate engraftment and function of HuCNS-SC cells in a well established rat model of the disease as preparatory studies for planned clinical trials. The research is expected to be concluded by year end, according to StemCells.

    More : http://www.genengnews.com/news/bnite...source=genwire
    http://justadollarplease.org/

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    "You kids and your cures, why back when I was injured they gave us a wheelchair and that's the way it was and we liked it!" Grumpy Old Man

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  2. #1322
    FRI., JAN 25, 2008 - 5:22 PM
    Keep politicians out of stem-cell science

    A Wisconsin State Journal editorial

    The work of world-renown scientist James Thomson and others at UW-Madison has made Wisconsin a leading center of stem-cell research.
    That research leadership has presented the state with a chance to also become a leading center for the translation of stem-cell research into businesses producing high-paying jobs for Wisconsin residents.

    It 's an opportunity the state cannot afford to squander.

    That 's why state lawmakers should have paid close attention to Gov. Jim Doyle 's State of the State speech this week, when he explained why Wisconsin has stayed at the forefront of stem-cell innovation:

    "Because we kept politicians out of it. "

    The politicians should remain out of it.

    more:

    http://www.madison.com/wsj/home/opin...9395&ntpid%3D1

  3. #1323
    Device able to pull stem cells from blood


    Published: Jan. 25, 2008 at 11:13 PM


    Font size:ROCHESTER, N.Y., Jan. 25 (UPI) -- A tiny, implantable device can pull adult stem cells out of a living rat with greater purity than any present technique, a U.S. study found.

    The device was designed by Michael R. King, who was studying how white blood cells, called neutrophils, know how to migrate to a point of infection. He observed that near an injury, the walls of the nearby blood vessels expressed an adhesive protein and if passing neutrophils brushed against selectins they stick to the vessel wall, but did remain struck, the neutrophils rolled to the site.

    more:
    http://www.upi.com/NewsTrack/Health/...om_blood/7082/

  4. #1324
    Stems here, stems there, stems cells in every part of our bodies. How doctors could not know this years ago?


    Scientists in stemcell world first

    26th January 2008, 11:30 WST



    Scientists from the University of WA have found readily available stemcells in human breast milk.

    The world-first discovery of a source of easily harvested stemcells promises to remove the ethical and practical barriers that now limit the extraction of the precursor cells from embryos and through cloning.

    Biomedical scientist Mark Cregan, who headed the work to be presented at next week’s international conference of the Society for Research on Human Milk and Lactation in Perth, said the findings of potentially reprogrammable breast and immune stemcells in human milk could lead to regeneration of some mammary tissues following surgery and treatments to overcome breastfeeding problems.

    more:

    http://www.thewest.com.au/default.as...ontentID=55998

  5. #1325
    Blind man now has partial vision thanks to stem cell surgery

    Posted

    By Elizabeth Donatelli

    LOUISVILLE (WAVE) -- A California man set world records skiing, worked as a CIA analyst, and inventor all while blind in both eyes. Now, after more than four decades of living life blind, a rare stem-cell surgery has given him the gift of sight. He can now see colors, shapes -- and his children for the first time. WAVE 3's Elizabeth Donatelli has his story.

    Mike May recalls the first time the darkness was lifted. "He took the bandages off and then woosh!" said Mike May. "All this light comes in, and I'm seeing somebody standing next to me like you and I'm seeing objects around and all this visual information starts flooding in at this incredible rate and I thought: 'Oh my gosh! I can see! This is amazing.

    more:

    http://www.wave3.com/Global/story.as...1&nav=menu31_6

  6. #1326
    Turning on adult stem cells may help repair bone

    Potential new approach to treating osteoporosis, other degenerative conditions

    The use of a drug to activate stem cells that differentiate into bone appears to cause regeneration of bone tissue and be may be a potential treatment strategy for osteoporosis, according to a report in the February 2008 Journal of Clinical Investigation. The study – led by researchers from Massachusetts General Hospital (MGH) and the Harvard Stem Cell Institute (HSCI) – found that treatment with a medication used to treat bone marrow cancer improved bone density in a mouse model of osteoporosis, apparently through its effect on the mesenchymal stem cells (MSCs) that differentiate into several types of tissues, according to a press release issued by EurekAlert

    more:

    http://www.thehindu.com/holnus/008200801261621.htm

  7. #1327
    Saturday, January 26, 2008 :: Alina Boey
    Adult Stem Cells Beneficial in Heart Failure Recovery

    Administration of adult bone marrow stem cells and mesenchymal stems cells can aid in the recovery of heart attacks,

    Melbourne, Australia - infoZine - A study in the Clinical and Experimental Pharmacology and Physiology published by Wiley-Blackwell shows that administration of adult bone marrow stem cells (BMC) and mesenchymal stems cells (MSC) can aid in the recovery of myocardial infarction (MI) - commonly known as heart attack - and consequently increase survival rates.

    The study - "Systemic Delivery of Adult Stem cells Improves Cardiac Function in Spontaneously Hypertensive Rats" - is designed to evaluate the impact of systemic delivery of BMC and MSC on spontaneously hypertensive rats induced with MI.

    more:

    http://www.infozine.com/news/stories...iew/sid/26649/

  8. #1328
    Money for stem cell research - Borough could be home to groundbreaking new therapies

    Two borough not-for-profit research institutions were among 25 institutions statewide to receive one-year development grants to support stem cell research and training.

    The SUNY Downstate Medical Center, 450 Clarkson Avenue in Flatbush, received $192,267, and Polytechnic University, 6 MetroTech Center in Downtown Brooklyn, re-ceived $100,000.

    The $14.5 million total in first grant awards comes through the state’s $600 million multi-year stem cell research initiative that Gov. Eliot Spitzer funded in the 2007-08 budget.

    “Innovative stem cell research has the potential to yield therapies that may prevent, treat and perhaps even cure many debilitating and life-threatening conditions,” said Spitzer.

    more:

    http://www.parkslopecourier.com/site...d=560112&rfi=6

  9. #1329
    Senior Member Bhaskar's Avatar
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    Diabetes: Pancreas Progenitors - several sources/contacts/photos

    Hurt an Organ, Help a Disease?

    Researchers report that by injuring an animal's pancreas, they have found a population of cells that naturally become insulin-producers. It's not clear whether the find will impact diabetes patients, but researchers are intrigued by the discovery and what it might reveal about the transformative ability of pancreatic cells.In people with diabetes, insulin-producing cells in the pancreas, called beta cells, have been destroyed or may behave sluggishly. This leaves the body unable to regulate its blood sugar. Coaxing the
    pancreas to make new beta cells is one of the great goals of diabetes research. Scientists debated for years whether the pancreas holds stem cells that could replenish beta cells, but in 2004, biologists led by Douglas Melton at Harvard looked for these stem cells in the pancreas of mice and failed to find them. His team instead reported that existing beta cells could multiply to form new ones (ScienceNOW, 5 May 2004).

    Harry Heimberg of Vrije Universiteit in Brussels, Belgium, wondered whether there were additional sources of new beta cells. Earlier experiments in rats had found that clamping a pancreatic duct and stopping digestive enzymes from entering the small intestine roughly doubles the mass of beta cells in the pancreas. But which cells in the pancreas were generating these extra beta cells?

    More : http://sciencenow.sciencemag.org/cgi...ull/2008/124/4

    http://www.sciam.com/article.cfm?id=...ncreas-healing

    http://www.eurekalert.org/pub_releas...-epp012508.php

  10. #1330
    Senior Member Bhaskar's Avatar
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    Osteop - turning on the bone makers

    Turning on adult stem cells may help repair bone
    Potential new approach to treating osteoporosis, other degenerative conditions
    The use of a drug to activate stem cells that differentiate into bone appears to cause regeneration of bone tissue and be may be a potential treatment strategy for osteoporosis, according to a report in the February 2008 Journal of Clinical Investigation. The study – led by researchers from Massachusetts General Hospital (MGH) and the Harvard Stem Cell Institute (HSCI) – found that treatment with a medication used to treat bone marrow cancer improved bone density in a mouse model of osteoporosis, apparently through its effect on the mesenchymal stem cells (MSCs) that differentiate into several types of tissues.

    "Stem cell therapies are often thought of as putting new cells into the body, but this study suggests that medications can turn on existing stem cells that reside in the body's tissues, acting as regenerative medicines to enhance the body's own repair mechanisms," says David Scadden, MD, director of the MGH Center for Regenerative Medicine and HSCI co-director. "Drugs that direct immature cells to become a particular cell type, like in this study, could potentially be very useful."

    More : http://www.eurekalert.org/pub_releas...-toa012508.php

    http://uk.reuters.com/article/health...37473620080125

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