The Signalling System In The Central Nervous System And Movement Control

Main Category: Neurology / Neuroscience News
Article Date: 19 Apr 2007 - 2:00 PDT
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Research by Renee Theiss, Jason Kuo and C J Heckman, which has just been published in The Journal of Physiology, throws light on how information is processed in the Central Nervous System (CNS) to drive movement. The findings are relevant to understanding mechanisms underlying movement and disorders such as spinal cord injury and motor neurone disease (ALS).

Interneurones in the spinal cord integrate command signals from the brain, with information from the senses, and their own internal pattern generating activities to send appropriate instructions to motorneurones controlling movement. Spinal interneurones exhibit a remarkable variety of firing patterns in response to a pulse of injected current, with important implications for information processing. These patterns range from repetitive to delayed, to bursting and to single spiking.

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