25 years of Embryonic Stem Cells
January 2007

In this focus
Current research
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Embryonal carcinoma cells
Embryonic stem cells

This year marks the 25th anniversary of two papers reporting the
first isolation of mouse ES cells. The first impact of the mouse ES
papers was enabling targeted gene knock outs in mice, a technology
which has revolutionized mouse genetics and developmental biology. It
took seventeen more years for Jamie Thomson to isolate ES cells from
human embryos, one of the great milestones in human biomedical

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