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Thread: Bowman-Birk Inhibitor Concentrate?

  1. #1

    Bowman-Birk Inhibitor Concentrate?

    Has this ever been considered for the treatment of SCI?

  2. #2
    Quote Originally Posted by antiquity
    Has this ever been considered for the treatment of SCI?
    Antiquity, it is the first time that I have heard of this substance. I'll look into it. My friend and colleague Kwok-Fai So at Hong Kong University is very interested in using natural substances. If it is true that a soybean substance would reverse or prevent mutliple sclerosis, we should be seeing a significantly less multiple sclerosis in populations that eat a lot of soybean in their diet. I wonder if this is true.


  3. #3
    It was this part that caught my eye. Sounds like it would have potential for acute SCI. Be sure to let us know what you find out!

    Dr. Rostami, who is also director of the Neuroimmunology Laboratory in the Department of Neurology at Jefferson Medical College, and his group used an animal model of experimental autoimmune encephalomyelitis (EAE), which mimics MS, to investigate BBIC's potential immune system-suppressing properties. BBIC inhibits proteases, enzymes that play important roles in the inflammation and demyelination processes that are at the heart of MS. It has been used for other conditions, notably precancerous conditions in the mouth.

    He and his co-workers compared two groups of animals with EAE. One group received BBIC, while the other received only an inert substance. "Animals that received BBIC were able to walk while those that didn't get the drug were not," he says. He notes that the animals aren't cured but can walk with some limp or weakness. "The results are promising because this is a safe, natural compound from soybean and is given orally."

    Further analysis revealed that the central nervous systems of animals that received BBIC showed "significantly less inflammation and demyelination" than those that didn't receive the therapy. "It's the first time that BBIC has been used in an EAE model and has shown significant disease suppression, and we hope it can eventually be used in humans," says Dr. Rostami. His group's next step is to design clinical trials in humans.
    Last edited by antiquity; 12-22-2006 at 02:20 AM.

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