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Thread: maxolon?

  1. #1
    Junior Member
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    maxolon?

    martin, what is the dosage and frequency of this medication are you taking?

    hc

  2. #2
    Junior Member
    Join Date
    Nov 2001
    Location
    BROCKTON
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    is anyone familiar with this medication?

  3. #3
    Harold,

    Maxolon or metoclopramide monohydride is drug that increases stomach and upper intestinal contractions to increase the speed of gastric emptying. It also seems to increase small intenstinal movements that reduces transit time of food but has no effect on gastric secretion or cardiovascular system. It works on the nicotinic receptor and is antagonized by atrophine-like drugs. It is usually used to treat gastric stasis and hypomotility of the gut. It also is useful for managing dyspepsia, flatulence, and post-vagotomy syndrome. It reduces nasuea and vomiting, suppresses chronic hiccups, and is sometimes used for upper GI x-rays with contrast to enhance visualization of the gut. It is used in children for severe intractable vomiting from a known cause.

    Dose should not exceed 0.5 mg/kg, especially for young children and young adults. Because vomiting and nausea may be caused by serious problems, it should not be used to treat nausea of unknown origin.

    Side effects include restlessness, anxiety, agitation, and occasionally acute depression. It may increase dystonia (posturing associated with abnormal brain activity) and muscle tone. Most of these symptoms occur early if they do and are gone within 24 hours of withdrawing the drug. In women, it may increased serum prolactin levels with breast engorgement and lactorrhea. Overdose can cause dyskinesia or abnormal movements and spasms, reversible with anti-Parkinson's drugs.

    The drug is made by SmithKline Beecham

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