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National Institute of Advanced Industrial Science and Technology (AIST), Osaka University Succeed in Creating Mesenchymal Stem Cell from Wisdom Tooth Germ

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Tokyo, Mar 8, 2006 (JCN) - The National Institute of Advanced Industrial Science and Technology (AIST) announced on March 7 that its Research Institute for Cell Engineering has established a method to creat a mesenchymal stem cell from tooth germs, in collaboration with Osaka University.

The new method, which uses a special protease, can isolate a mesenchymal stem cell from tooth germs of extracted wisdom teeth.

In in vitro experiments, the two partners differentiated and induced the isolated cells into bone, liver and nerves. Further, in mice experiments, they succeeded in regenerating bone tissues and liver using the isolated cells. These findings indicate that tooth germs, which are usually discarded after extraction, will be a promising material in the regenerative medicine.

Details of the achievement will be presented at the 5th Annual Congress of the Japanese Society for Regenerative Medicine.