My son, 23, has been a C-6 quad for the past three years. Vacation planning has not been easy, but I can say that our trip to Las Vegas last month was worth it.
We stayed at Caesar's, and the bathroom (his main concern) not only met his needs, it was luxorious as well. I had called ahead for measurements to be sure that the rehab shower chair would back over the toilet (it did), and that the roll-in shower would accommodate the rehab chair (it did as well).
Since we were traveling from the Northeast, I needed to rent a rehab shower chair. Caesar's gave me the name of a medical supply company, Desert Medical, and they delivered the chair to the hotel. The chair happened to be the exact one my son uses at home, and was brand new (clean).
We all had a great time, and the only disappointment my son had was not being able to get into the pool. He sat in the sun and sprayed himself with water to stay cool. He likes to play cards, and everything was accessible to him. He was able to go to visit the other hotels in the area easily. The section of town where we stayed was very wheel chair friendly. I would recommend a trip to Las Vegas any time!