Reasons for Complications with Kidney Failure Patients

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Mayo Clinic researchers searching for explanations of high mortality rates among kidney failure patients undergoing hemodialysis are focusing their attention on the use of heparin, a drug used to reduce clotting of the blood.




Newswise — Mayo Clinic researchers searching for explanations of high mortality rates among kidney failure patients undergoing hemodialysis are focusing their attention on the use of heparin, a drug used to reduce clotting of the blood.

Their study in the August issue of Mayo Clinic Proceedings is a preliminary look at one aspect affecting the health of patients who undergo hemodialysis. In the study, they found patients who had a higher level of adverse outcomes also had elevated levels of heparin antibodies in their blood. The authors believe this is the first study examining this association.

However, Robert McBane, M.D., a Mayo Clinic cardiovascular disease specialist who led the study, cautions that these results are preliminary.

“These results are thought-provoking and hypothesis-generating, but at this point we need more study,” says Dr. McBane. “Patients requiring hemodialysis have a high mortality rate for reasons which are not clear. The search for variables contributing to this mortality rate is of prime importance.”

Heparin is an anticoagulant, which is usually used to prevent the formation of blood clots in the blood vessels that can prove harmful.


http://www.newswise.com/articles/view/513845/