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Thread: Panel: Drug Maker Not at Fault for Oxycontin Abuse

  1. #1

    Panel: Drug Maker Not at Fault for Oxycontin Abuse

    Found on Yahoo! Health news
    http://story.news.yahoo.com/news?tmp...07/hl_nm/oxy_1

    Glad to see this position getting some press.

    David Berg

    ----------------------------
    Panel: Drug Maker Not at Fault for Oxycontin Abuse
    Thu Feb 7, 5:35 PM ET

    WASHINGTON (Reuters Health) - Panelists convened here Thursday by the American Enterprise Institute (AEI), a conservative think tank, mostly concurred that drug maker Purdue Pharma should not be held solely responsible for abuse of its long-acting pain killer OxyContin.


    Only one panelist, a journalist from a West Virginia newspaper, said the company should do more to keep the drug out of the hands of abusers.

    Greg Stone wrote a series about OxyContin abuse in his community last year for the Charleston Gazette. Stone said the problem continues unabated, citing an arrest in Charleston just days ago of two men who had arrived from Baltimore with 10,000 OxyContin pills in their vehicle and a recent interview with a woman who said she was injecting 400 milligrams of OxyContin--with a street value of $400--daily.

    This kind of abuse would not be possible with other forms of opioids, Stone maintained.

    "It raises the question of manufacturer responsibility when you're holding something that explosive," he said.

    Stone suggested that unless OxyContin could be reformulated to discourage abuse, it should perhaps be taken off the market.

    Purdue Pharma senior medical director for health policy J. David Haddox told the meeting that the company is studying a pairing of OxyContin, known generically as oxycodone, with naloxone or some other agent to lessen the "high." But it is proving technically difficult, he said, noting that the company has to determine how much naloxone it can safely add without neutralizing the legitimate pain-killing effect.

    OxyContin reportedly is being abused more than other opioids. But that notion--and the perception that the drug is causing more deaths--has been debated because overdose victims usually have other substances in their systems. And, since oxycodone is in other prescription medications, such as Percocet, OxyContin can't be definitely fingered as the culprit.

    Haddox said no data suggests that OxyContin is any more addictive than other opioids.

    The company has been criticized for what some see as aggressive marketing, which may have raised OxyContin's profile in the eyes of potential abusers. But Haddox said, "I don't accept the premise that aggressive marketing is bad," adding that the company was seeking to address the problem of under-use of medications for pain.

    Sally Satel, an AEI fellow and psychiatrist who works at a methadone clinic in Washington DC, said that Purdue was not creating addicts, either through marketing or insufficient monitoring. Satel is known for her controversial position that people choose to be addicts.

    "Compulsive use often has tragic consequences, but that's not the fault of the drug," said Satel.

    She and several other panelists said they believed that OxyContin abuse was limited to several regions of the country, and that there was a bit of an overreaction in the media. But an audience member cited data he claimed showed that use of the drug was spreading throughout the country.

    Another audience member, a substance abuse specialist, suggested the company could have foreseen a potential for OxyContin abuse, given the rising trend in prescription drug abuse when OxyContin was introduced in 1995. He said the company, distributors, and pharmacies should do more to monitor sales and dispensing.

    Panelists said it was likely that OxyContin abuse would remain a law enforcement, not a company or medical issue. Since the drug is on the market, the Food and Drug Administration (FDA) has no legal authority to remove it or enforce restrictions on access because of the diversion issue, said Erika King, a food and drug law attorney with Covington & Burling in Washington DC.

    The agency could pressure the company to further restrict access, she noted, but added that she, too, did not think Purdue should be held responsible for the abuse and diversion of OxyContin.

  2. #2
    Purdue Pharma pushed that drug HARD on docs. My doc pushed it on me with VERY specific instructions on how to use it. As a side note, I noticed my pharmacist had a freaking gun on his hip fully exposed when I went there the other day. I bet you all know why...
    OC is a good drug if used properly, but too many peeps found out too quickly the pleasurable "side effects." I don't take it anymore (plus it constipates), but I wouldn't necessarily blame the manufacturer either. It is a nasty withdrawal, too.



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  3. #3
    Senior Member craig's Avatar
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    Big Deal

    [QUOTE]Originally posted by offthahook:

    Purdue Pharma pushed that drug HARD on docs. My doc pushed it on me with VERY specific instructions on how to use it. As a side note, I noticed my pharmacist had a freaking gun on his hip fully exposed when I went there the other day. I bet you all know why...
    OC is a good drug if used properly, but too many peeps found out too quickly the pleasurable "side effects." I don't take it anymore (plus it constipates), but I wouldn't necessarily blame the manufacturer either. It is a nasty withdrawal, too.


    40mg. Works fine for me, its just not for some ppl.

    [This message was edited by craig on Feb 19, 2002 at 03:26 PM.]

  4. #4
    Senior Member craig's Avatar
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    oxycontin

    Ya know what I mean , if you are weak and can't control your drug use you should stay away from oxycontin. Find another way but don't trash the medication that works for some ppl.

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