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Thread: Long-Time Pot Users Show Mental Deficits

  1. #1

    Long-Time Pot Users Show Mental Deficits

    Long-Time Pot Users Show Mental Deficits
    Tue Mar 5, 5:37 PM ET
    By Amy Norton

    NEW YORK (Reuters Health) - Long-time, heavy marijuana users may eventually see their memory and attention span go up in smoke, new research suggests.

    Investigators found that, among pot smokers seeking treatment for marijuana dependence, long-time users performed more poorly on tests of memory and attention than shorter-term users and non-users.

    The findings show that over time, marijuana smoking can cause intellectual impairments that "endure beyond the period of intoxication" and worsen the longer a person uses the drug, the study authors report in the March 6th issue of The Journal of the American Medical Association.

    But another researcher not involved in the study pointed to shortcomings in the work that he says make it tough to draw that conclusion.

    In an accompanying editorial, Dr. Harrison G. Pope, Jr. notes that marijuana users who seek drug treatment do not necessarily reflect users in general, since these individuals may have other health issues such as anxiety or depression.

    In the study, researchers led by Dr. Nadia Solowij of the University of New South Wales in Sydney, Australia studied 102 pot-smoking Americans and 33 non-users. Marijuana users typically smoked every day, with long-time users doing so for an average of 24 years. Shorter-term users had smoked for about 10 years, on average. The vast majority said that they currently were not using other drugs, or did so only occasionally.

    Results of the mental functioning tests--taken after at least 12 hours of abstinence--showed that long-time users performed less well than shorter-term users and non-users.

    "We found that long-term users had problems with learning, storage of learned information and retrieval of information from memory," Solowij told Reuters Health.

    This does not mean the drug caused brain damage in these cases, she said, explaining that the impairments seen in long-time users were "relatively subtle."

    Still, Solowij noted, the deficits could affect daily functioning--hindering, for example, a person's ability to study or remember an item he or she just read.

    But although such deficits, if prolonged or irreversible, would be of "grave concern," other studies have found no such impairments in long-time marijuana users, according to Pope, a researcher at Harvard Medical School and McLean Hospital in Belmont, Massachusetts.

    Pope and his colleagues recently found "virtually no significant differences" between heavy marijuana users and non-users on a battery of neuropsychological tests.

    Part of the difficulty in sizing up the impact of marijuana is weeding the drug's effects out from the "background noise" of other factors, like psychiatric problems and abuse of other drugs, according to Pope. In this study, nearly half of the long-time marijuana users had in the past regularly used or abused alcohol or other drugs.

    But there are also plausible biological reasons for why sustained marijuana use could affect things like memory. Solowij noted that the brain receptors the drug acts on exist in large numbers in regions involved in memory. Over the years, she said, marijuana exposure might change the way these receptors and other brain chemicals operate.

    According to Pope, it seems almost certain that marijuana produces short-lasting mental deficits, but whether they endure or worsen over time is still unclear.

    Also unknown is whether any impairments are reversed after a person stops smoking pot, Solowij pointed out.

    "We do not yet know whether the impairments recover after stopping or reducing (marijuana) use," she said. "We are currently investigating this question."

    SOURCE: The Journal of the American Medical Association 2002;287:1123-

  2. #2

    Pot Bad for Memory? Get Out!

    I'm glad precious research dollars are being spent in such ground breaking areas.

    Next, I think we should spend thousands on a controlled and normalized double blind study to determine whether exercise is really beneficial.

  3. #3

    No kidding

    I can't believe the studies that people do when any average person could tell them the results! Like today I heard this groundbreaking news that breathing pollution causes lung s$*% sherlock...

    "Each moment in time we have it all, even when we think we don't."
    --Melody Beattie, writer and counselor

  4. #4
    Senior Member
    Join Date
    Oct 2001


    yes think we knew that,

  5. #5
    Senior Member JimD's Avatar
    Join Date
    Dec 2001
    Long Island, NY
    Here's another one: I once saw a study of college students that made the astonishing discovery (are you ready?) that increased alcohol consumption led to an increase in casual sex!

    Someone had to do a study to find that out?
    (Actually, I guess I spent four years in college studying it myself :-)

  6. #6
    I was on the five year plan myself Jim.

    Where in Long Island are you from? I have relatives from Lynbrook and Oceanside.

    ... ...

  7. #7


    Uh, um um i forgot, forget it.

  8. #8
    Senior Member JimD's Avatar
    Join Date
    Dec 2001
    Long Island, NY

    Hi JLB

    I'm from New Hyde Park - it's in central Nassau county - maybe 15 or 20 minutes from your relatives. And hey, the 5 year plan is a great option - it's just another year of 'research'!

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