Source:

Public Library Of Science
Date:

2003-12-22
Profiling The Genes That Make Stem Cells

While the controversy surrounding the ethics of stem cell research shows no signs of abating, scientists continue to demonstrate the promise of stem cell-derived therapies for a wide range of degenerative diseases. The hope is that stem cells, which retain a unique "pluripotent" ability to morph into any of the 200 cell types of the human body, could be used to repair or replace damaged or diseased tissue. However, little is known about the molecular events that trigger this differentiation of stem cells. In this issue of PLoS Biology, Minoru Ko and colleagues present a model that takes a first step towards characterizing the molecular profile of stem cells, based on a comprehensive database of genes expressed in mouse early embryos and stem cells.

See rest of (short) article here.