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Thread: Eusol and Kringle Pharma

  1. #1

    Eusol and Kringle Pharma

    To the best of my knowledge Eusol and Kriingle Pharma have not received much attention here -- would like to get your perspective on the advancements of these two companies; have you heard of them? Do you think it is promising? Any additional information available?

    Eusol -- they are already in phase III
    https://en.eusol-biotech.com.tw/service.php

    "ES135 is a recombinant human acidic fibroblast growth factor (rhFGF1) with 135 amino acids. With its effect to promote neurite outgrowth, ES135 can be applied to the medical use of repairing neuron function. The sequence of ES135 has been patented in Taiwan, EU, China and the United States. A multi-center, double blind, randomized, placebo control study as the pivotal Phase 3 clinical trial for spinal cord injury is on-going."

    Kringle Pharma -- completed phase I/II for acute SCI (hopefully it can be translated to chronic SCI)
    http://www.kringle-pharma.com/en/


    "Phase I/II study of recombinant human HGF, KP-100IT, for acute spinal cord injury was completed, and the clinical study report has been issued. The positive results of this study will be published later in a scientific journal and presented at academic conferences."
    "KP-100IT, recombinant human HGF for the treatment of acute spinal cord injury, was designated as an orphan drug in Japan as of September 12, 2019, with the approval of the Minister of Health, Labor and Welfare."


  2. #2
    Very interesting. I tried emailing the place in Taiwan and email was rejected. We may need more local people to help us find out more about them....

  3. #3
    Junior Member
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    The inventor of ES135 is Henrich Chen, he has been mentioned in CC forum many times.
    https://www.ym.edu.tw/phd/HCheng_new.htm


    For your reference:
    http://www.cpmda.org.tw/news_show_n1.php?news_id=8706

    ("雅祥" = Eusol, "華碩" = ASUS, yes, a notebook big manufacturer, "鄭宏志"= Henrich Chen. Sorry my poor English, Google translation please. )

    The effects of ES135..........,no comments.
    Last edited by Jyi; 11-29-2019 at 03:54 AM.

  4. #4
    Thanks, jyi! What is considered 'serious spinal cord injury'? I think they all are serious heh. Wouldn't it be a good idea to try drug on people who could respond better such as incomplete injuries? -Jan

  5. #5
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    Quote Originally Posted by FellowHawkeye View Post
    Thanks, jyi! What is considered 'serious spinal cord injury'? I think they all are serious heh. Wouldn't it be a good idea to try drug on people who could respond better such as incomplete injuries? -Jan
    It's a machine translation error, 嚴重的脊髓損傷 'serious' should be corrected by 'severe'.

  6. #6
    Quote Originally Posted by Jyi View Post
    It's a machine translation error, 嚴重的脊髓損傷 'serious' should be corrected by 'severe'.
    Okay, then completely paralyzed...

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