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Thread: Needing Intravenous IV for Bladder-UTI Infection

  1. #11
    Gentamicin/tobramycin instillation articles:

    This is Canadian Urological Assoc study re: gentamicin instillation - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798439/

    Lit review of instillation research - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097067/

    Urotoday video & notes - https://www.urotoday.com/video-lectu...-17-09-07.html

    Univ of Michigan urology dept instructions for instillation - http://www.med.umich.edu/1libr/urolo...Indwelling.pdf

    instructions for home compounding and instillation, Seattle Children’s - https://www.seattlechildrens.org/pdf/PE1769.pdf

    university of Louisville is currently running a clinical trial of instillation for SCI folks.

    P Aeruginosa articles, etc.

    Merck manuals overview on pseudomonas aeruginosa - https://www.merckmanuals.com/home/in...nas-infections


    CDC info sheet on Pseudomonas - https://www.cdc.gov/hai/organisms/pseudomonas.html - most common source in community is poorly maintained swimming pools and hot tubs.

    More pseudomonas - https://www.cdc.gov/hai/organisms/pseudomonas.html

    research from *1974* - pseudomonas in 24% of soil samples, only 0.13% of vegetable samples - https://aem.asm.org/content/aem/28/6/987.full.pdf.


    I strongly encourage anyone with c diff or p aeruginosa to find an experienced and SCI knowledgeable infectious disease doctor. I had a lot of super nice, very comforting and not at all knowledgeable urologists and ID folks in the first 18 months post-injury discharge and the consequences of that misplaced trust have been pretty miserable.

  2. #12
    Senior Member ChesBay's Avatar
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    Quote Originally Posted by annev308 View Post
    Gentamicin/tobramycin instillation articles:

    This is Canadian Urological Assoc study re: gentamicin instillation - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798439/

    Lit review of instillation research - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097067/

    Urotoday video & notes - https://www.urotoday.com/video-lectu...-17-09-07.html

    Univ of Michigan urology dept instructions for instillation - http://www.med.umich.edu/1libr/urolo...Indwelling.pdf

    instructions for home compounding and instillation, Seattle Children’s - https://www.seattlechildrens.org/pdf/PE1769.pdf

    university of Louisville is currently running a clinical trial of instillation for SCI folks.

    P Aeruginosa articles, etc.

    Merck manuals overview on pseudomonas aeruginosa - https://www.merckmanuals.com/home/in...nas-infections


    CDC info sheet on Pseudomonas - https://www.cdc.gov/hai/organisms/pseudomonas.html - most common source in community is poorly maintained swimming pools and hot tubs.

    More pseudomonas - https://www.cdc.gov/hai/organisms/pseudomonas.html

    research from *1974* - pseudomonas in 24% of soil samples, only 0.13% of vegetable samples - https://aem.asm.org/content/aem/28/6/987.full.pdf.


    I strongly encourage anyone with c diff or p aeruginosa to find an experienced and SCI knowledgeable infectious disease doctor. I had a lot of super nice, very comforting and not at all knowledgeable urologists and ID folks in the first 18 months post-injury discharge and the consequences of that misplaced trust have been pretty miserable.
    Great post. A lot of good info. Thanks

  3. #13
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    Quote Originally Posted by annev308 View Post
    I strongly encourage anyone with c diff or p aeruginosa to find an experienced and SCI knowledgeable infectious disease doctor
    Yes that would be ideal, unfortunately SCI knowledgeable specialists seem to be in short supply especially in smaller centres like mine. Thanks for posting the articles, hopefully they will be willing to listen.

  4. #14
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    Exclamation

    Its now been 4 days since I finished the 7 days of the antibiotic mirepenem via IV a Pseudomonas infection of my bladder. I have been feeling much better the past few days with far less bladder spasms and pain.

    As I write this I am concerned the infection isnt gone and is coming back to torment me. some of the symptoms of a bladder infection I had before are returning like bladder spasms and emptying of my bladder but not quite as bad, at least not yet. I read of other people?s experiences where they need more than 1 course of IV antibiotics to treat some infections. I did have two cultures taken this morning so I will update when I find out if I still have the infection or am cleared.

  5. #15
    I had multidrug resistant pseudomonas for 6 years. I spent at least 14 months on IV antibiotics to “manage” the infection -no one ever encouraged me to think we might be rid of it. It was basically a juggling act of trying to control the population so that I could still have a life with the infection. It is a highly adaptive organism and the biofilm it forms can make treatment very challenging.

  6. #16
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    I have a good update to share. After seven days of intravenous The pseudomonas bacteria infection I had seems to be cleared up and out of my life. My bladder and quality-of-life is better since Im not peeing my pants just about every time I get up and dressed.
    C4/5 incomplete, 17 years since injury

    "The trick is in what one emphasizes. We either make ourselves miserable, or we make ourselves happy. The amount of work is the same.” - Carlos Castaneda

    "We live not alone but chained to a creature of a different kingdom: our body." - Marcel Proust

  7. #17
    I had a similar experience one and a half years ago. After experiencing UTI symptoms I had my urine cultured. My urologist told me that the infection could not be treated with oral antibiotics. He referred me to a infectious disease specialist. I made an appointment with the specialist. but prior to I instilled microcyn in my bladder on three different ocations. Evening, morning, evening. After that I submitted another urine sample. The result was that the infection was gone. I kept the appointment with the specialist but did not take any antibiotics. That was one and a half years ago and I frequently flush my bladder With microcyn and it seems to work. I also drink a lot of water. On average about 4 to 5 L a day.

  8. #18
    Quote Originally Posted by KyleP2112 View Post
    I have a good update to share. After seven days of intravenous The pseudomonas bacteria infection I had seems to be cleared up and out of my life. My bladder and quality-of-life is better since Im not peeing my pants just about every time I get up and dressed.
    Hopefully this has eradicated the pseudomonas. You should get another urine culture and sensitivity done about a week after you have finished the IV antibiotics to be sure. If it has come back (same strain) then you need to be evaluated for conditions that can harbor bacteria in your urinary tract, including stones, abscesses, and prostatitis.

    (KLD)
    The SCI-Nurses are advanced practice nurses specializing in SCI/D care. They are available to answer questions, provide education, and make suggestions which you should always discuss with your physician/primary health care provider before implementing. Medical diagnosis is not provided, nor do the SCI-Nurses provide nursing or medical care through their responses on the CareCure forums.

  9. #19
    Quote Originally Posted by roll170 View Post
    I also drink a lot of water. On average about 4 to 5 L a day.
    Be very careful that you don't get hyponatremia (low blood sodium levels) drinking that much. 3 liters daily should be sufficient to flush your urinary tract.

    (KLD)
    The SCI-Nurses are advanced practice nurses specializing in SCI/D care. They are available to answer questions, provide education, and make suggestions which you should always discuss with your physician/primary health care provider before implementing. Medical diagnosis is not provided, nor do the SCI-Nurses provide nursing or medical care through their responses on the CareCure forums.

  10. #20
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    Quote Originally Posted by SCI-Nurse View Post
    Hopefully this has eradicated the pseudomonas. You should get another urine culture and sensitivity done about a week after you have finished the IV antibiotics to be sure. If it has come back (same strain) then you need to be evaluated for conditions that can harbor bacteria in your urinary tract, including stones, abscesses, and prostatitis.

    (KLD)
    My urologist was on top of things and didn’t take the PICC line out until a urine culture came back clear of the Pseudomonas after seven days of taking IV antibiotics. Besides I would have made sure I had a clear urine culture to be sure The infection was gone.
    C4/5 incomplete, 17 years since injury

    "The trick is in what one emphasizes. We either make ourselves miserable, or we make ourselves happy. The amount of work is the same.” - Carlos Castaneda

    "We live not alone but chained to a creature of a different kingdom: our body." - Marcel Proust

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