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Thread: UCSD Scientists Demonstrate Use of 3D Printing with Stem Cells

  1. #1

    UCSD Scientists Demonstrate Use of 3D Printing with Stem Cells

    Times of San Diego, January 15th, 2019 by Chris Jennewein

    UCSD Scientists Demonstrate Use of 3D Printing with Stem Cells for Spinal Repair

    UC San Diego medical researchers have for the first time used 3D printing technology to create a spinal cord and implant it with neural stem cells into rats with spinal cord injuries, the university announced Monday.

    The implant is designed to promote nerve growth and regrowth for victims of severe spinal cord injuries, according to the researchers. For the rats in the study, the 3D printed spinal cords spurred tissue growth, the regeneration of nerve cell extensions called axons and expansion of the implanted neural stem cells into the rat's natural spinal cord.

    The research appears in Monday?s issue of the journal Nature Medicine.

    "The new work puts us even closer to real thing," said Jacob Koffler, the study's co-first author. "The 3D scaffolding recapitulates the slender, bundled arrays of axons in the spinal cord. It helps organize regenerating axons to replicate the anatomy of the pre-injured spinal cord."

    For the rest of this story: https://timesofsandiego.com/tech/201...CrqcJScx0BtycA

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  2. #2
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    Wow. I'll chase the link but I assume the rats didn't recover much function or that would have been mentioned.
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    Senior Member NW-Will's Avatar
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    Made the Dailymail ! https://www.dailymail.co.uk/health/a...inal-cord.html
    If only we were rats!

    Don't rats recover function anyway ? and when they say walk again... do they mean stumble like a drunk ?
    Last edited by NW-Will; 01-16-2019 at 08:01 PM.

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    I think the 3D printed to size implant with stem cells intergrated is part of the cure, pair this with ISP protein injection and a couple months of therapy covers most of the bases possible.

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    Senior Member lunasicc42's Avatar
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    Quote Originally Posted by shitrock4 View Post
    I think the 3D printed to size implant with stem cells intergrated is part of the cure, pair this with ISP protein injection and a couple months of therapy covers most of the bases possible.

    Hello shitrock... Awesome name, welcome to the community
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  7. #7
    Quote Originally Posted by GRAMMY View Post
    It sounds like a great idea, and makes loads of sense.

    Unfortunately they seem to be going the same path to a long long process.

    The UCSD team continues to work on further improvements, including the addition of growth factors or other ingredients that may further encourage neuron growth and functional recovery. If all goes well, the team hopes to launch human clinical trials of their cell-based treatments for spinal cord injury within a few years.
    If they think it works, why not go to human trials with what they have now, and refine it in parallel.

  8. #8
    Senior Member Moe's Avatar
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    To me it sounds just as realistic as the head transplant article.
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  9. #9
    Quote Originally Posted by niallel View Post
    If they think it works, why not go to human trials with what they have now, and refine it in parallel.
    Considering the cost and time involved in human clinical trials, it wouldn't make sense to test a product for market that may need additional growth factors or other key ingredients. A car with 3-1/2 wheels wouldn't perform and sell very well, right? (They'll only have one shot. They best try to make it a viable product).

  10. #10
    Senior Member Moe's Avatar
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    why not just inject the growth factors alone to the original cord, in most sci cases there's no 'gap' to fill in a 3D printed cord unless you cut and 'glue' both ends, even if succes printing a real cord, makes no sense to fuse 2 cuts instead of 1... Media hype at its best, thats why rats are used since they cant defend themselves IMO. Great marketing technique to free publicity to raise funds that may lead nowhere except money in the pockets... just pisses me off
    Last edited by Moe; 06-10-2019 at 11:24 AM.
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