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Thread: Paralyzed mice with spinal cord injury made to walk again.

  1. #1
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    Paralyzed mice with spinal cord injury made to walk again.

    Please forgive me if this has already been posted.

    https://www.sciencedaily.com/release...0719142035.htm

  2. #2
    Just had one of my PCAs who is a physical therapist tell me about this one less than 12 hours ago, looks promising.

    A drug that can simulate the gains made with the effects of epidural electrical stimulation, with a pacemaker of sorts attached to your back, is absolutely the way to go, could be close to what might be the most appropriate route.

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    Combining this chemistry with transcutaneous stim could be very good stuff.
    T3 complete since Sept 2015.

  4. #4
    Acute injuries in the mice almost certainly unfortunately

  5. #5
    Very interesting. Wesmaister found what looks to be CLP290 being sold online so my question is must it be injected and can it be more helpful to people with incomplete injuries. -Jan

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    Senior Member Oddity's Avatar
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    Ahhhhhh...what a time to be a mouse. Must be nice.
    "If you only know your side of an issue, you know nothing." -John Stuart Mill, On Liberty

    "Even what those with the greatest reputation for knowing it all claim to understand and defend are but opinions..." -Heraclitus, Fragments

  7. #7
    Are the cured mice reproducing?

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    Quote Originally Posted by Oddity View Post
    Ahhhhhh...what a time to be a mouse. Must be nice.
    CC regularly makes me envious of mice and rats. Must be nice to be the obvious cure priority.
    I hear insurance for mice even covers commode chairs.
    T3 complete since Sept 2015.

  9. #9
    Hey Mize, Do you think first treatment with CLP290 and than Parastep training?

    Quote Originally Posted by Mize View Post
    Combining this chemistry with transcutaneous stim could be very good stuff.
    www.MiracleofWalk.com

    Miracles are not contrary to nature, but only contrary
    to what we know about nature
    Saint Augustine

  10. #10
    Senior Member Tim C.'s Avatar
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    Quote Originally Posted by lunasicc42 View Post
    However that prediction of 5 years might be true
    I LOVE seeing references to the " five year " plan.
    When I got into the "cure watch" thing in the months following my injury in 2002, my SCI Doctor, super intelligent, well respected, cure oriented scientific type, he used the "5 year" prediction as well...but always held back when it came to defining "cure" as near full recovery, but he did clearly project "significant improvements" within a 3 to 5 year period. Especially upon introducing me to C. Reeve and both inviting me to meet with Wise and visit the Keck Center SCI program claiming that international research collaboration along with CR's star power will soon yield significant advancements towards the cure. Still, and this was back when just the mere thought of living quad for even 6 months was enough to strike fear and panic in me. I immersed myself into contributing in any way I could, even going overseas to join in the OEG cell clinical trials: spending contributions from friends and neighborhood fundraisers just to be a guinea pig. I think the whole anti-stem cell thing in the US actually served to increase the press coverage for those of us suffering from SCI. The Internet was full of encouraging news of potential cure breakthroughs being studied in all corners of the world. More and more broken-necked rats were recovering each day, albeit it won't happen overnight for we humans. OK, I reasoned with myself, SCI is a complicated condition, I may have to accept the unthinkabLe and stick out the full 5 years to get my body back, after all it wasn't all that long ago that spinal injuries were a guaranteed death sentence, for sure as severe an injury like mine...so buck up buckeroo and deal with it.
    Fast forward to 2018, most people think the first Superman remake was G. Clooney, more research is dedicated to cyber bullying, erectile disfunction and obesity than SCI. Those SCI cases making the network news do so only because their positive upbeat attitudes, preaching their dogged determination to someday walk again,despite their "remaining life in a wheelchair" diagnosis makes good journalistic human-interest stories, or "person of the week" clip to fill in the last five minutes of the news report. Several reports however do come out under the "new in technology" corner of the news hour spotlighting mechanized attachments for the walking-challenged to become real-life robocops.....but not one story on any incremental recovery.
    That will happen in five more years, stay tuned.

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