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  1. #1

    RENETX Update

    From their website last month:

    News Image
    NEW HAVEN, CONN. (PRWEB) MAY 07, 2018

    The Economic Development Corporation of New Haven announced today that New Haven-based ReNetX Bio, Inc., a private biotech company, has closed on its Series A funding and also solidified the relationship that the company has had with the city. The company plans to begin clinical trials on its drug within the year.

    ReNetX Bio, Inc.?s mission is to provide first-in-class therapeutics to treat injury and damage to the central nervous system (CNS) in conditions such as spinal cord injury (SCI), stroke, and glaucoma. The company was founded based on the innovative technology from Dr. Stephen Strittmatter's work at Yale University to restore neurologic function after CNS injury.

    The technology allows neurons in the brain to regrow by inhibiting factors that prevent its regeneration. This technology platform provides hope for patients with spinal cord injuries, stroke and glaucoma.

    ?ReNetX Bio?s decision to open its corporate headquarters in New Haven continues to advance the city?s strong reputation as a center of innovation and jobs,? stated New Haven Mayor Toni N. Harp. ?New Haven is committed to providing a strong working environment for ReNetX Bio and other biomedical and high-tech startups as they grow their companies and make New Haven their home.?

    ReNetX Bio completed Series A funding with Spring Mountain Capital and Connecticut Innovations co-leading the round. The funding round was oversubscribed, a testament to the potential of the technology platform. ReNetX Bio also raised $7MM in 2017 from The Wings of Life Foundation which is dedicated to finding a cure for spinal cord injury

    ?We believe that ReNetX Bio?s fusion protein, AXER-204, shows promising potential to treat chronic spinal cord injuries, a significant unmet need,? stated Gregory P. Ho, President, Spring Mountain Capital. ?We enthusiastically support the company?s Founder and its very experienced management team in their pursuit of this very important mission.?

    ?ReNetX Bio is well positioned for growth and New Haven is where we want to grow,? stated Erika R. Smith, CEO, ReNetX Bio. ?New Haven has become a thriving hub for biotech companies bringing talent, innovative science and a dynamic community. We are excited to contribute to the City?s growing reputation as a highly desirable location for companies focusing on providing solutions to 21st century challenges.?

    ?Connecticut Innovations is committed to proving capital and strategic guidance to growing high-tech companies in Connecticut, stated David Wurzer, Executive Vice President and Chief Investment Officer of Connecticut Innovations. ?We?re proud to support ReNetX Bio and their ground-breaking work as they continue to innovate and grow in Connecticut.?

    ?ReNetX Bio?s commitment to New Haven is further proof that New Haven has the work force and business environment to support biomedical and high-tech companies,? stated Ginny Kozlowski, CEO of the Economic Development Corporation of New Haven. ?We appreciate their commitment to the City and look forward to working collaboratively with them as they grow jobs in our city and develop therapeutics for unmet medical needs.?


    I'd really like to participate in their trial, but especially if I could get the drug half the time at least......

  2. #2
    I am watching this one too, partly because I live not far away and partly because I like the body healing itself without introducing foreign cells. But, I think it is going to be difficult to compare the results of competing trials without some known constants like every trial utilizing the same physical therapy routine whether it’s the 6:6:6 plan or something else.
    please . . .test what you already know; and give us what you have. we may not be dying, but we certainly are not living either

  3. #3
    Did Human clinical trials begin as expected with this companys new drug (Nogo receptor blocker) in 2018?

  4. #4
    I was told the following last month:

    The Axer-204 Phase I trial has been delayed due to regulatory issues. The “issues” are totally workable but just take a bit of time. We are hoping the Phase I will begin in 2019Q1.

  5. #5
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    Anybody have any updates on the trials?

  6. #6

  7. #7
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    Indeed, throughout the US, basic research has slowed to a crawl as a result of the current government, particularly the Executive. People don't realize how much our scientific community relies on both basic research coming out of government labs, but also both regulatory (FDA, EPA, etc) and financial (SBIR, BAA, etc.) dependence.

    What most people don't realize is that corporations don't so basic research (the stuff that comes way before animal trials etc.); this part of the research pipeline is very high risk (maybe 1% success rate) so doing it gets boards of directors sued by their shareholders. Basic research is largely government funded and conducted at universities, national laboratories (this are run by private companies but funded by the Federal gov't), and government labs.

    If you ever want to see a cure for SCI, best to support the scientific community. Just a thought.
    T3 complete since Sept 2015.

  8. #8
    Quote Originally Posted by Mize View Post
    Indeed, throughout the US, basic research has slowed to a crawl as a result of the current government, particularly the Executive. People don't realize how much our scientific community relies on both basic research coming out of government labs, but also both regulatory (FDA, EPA, etc) and financial (SBIR, BAA, etc.) dependence.

    What most people don't realize is that corporations don't do basic research (the stuff that comes way before animal trials etc.); this part of the research pipeline is very high risk (maybe 1% success rate) so doing it gets boards of directors sued by their shareholders. Basic research is largely government funded and conducted at universities, national laboratories (this are run by private companies but funded by the Federal gov't), and government labs.

    If you ever want to see a cure for SCI, best to support the scientific community. Just a thought.
    That's the fact. Success has to first come from the science and research being done at the bench. If that hasn't been accomplished, there's no need to worry about patents, licensing, lobbyists, corporations, insurance or mountain of other moot points.

  9. #9
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    Any updates on when the clinical trials will be starting?

  10. #10
    Quote Originally Posted by RyanJ View Post
    Any updates on when the clinical trials will be starting?
    They say to send a message and they will respond to it. LINK

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