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Thread: Wise Young shows CNS regeneration using umbilical cord blood mononuclear cells

  1. #21
    Senior Member lunasicc42's Avatar
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  2. #22
    Senior Member lunasicc42's Avatar
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    bump... Jim
    "That's not smog! It's SMUG!! " - randy marsh, southpark

    "what???? , you don't 'all' wear a poop sac?.... DAMNIT BONNIE, YOU LIED TO ME ABOUT THE POOP SAC!!!! "


    2010 SCINet Clinical Trial Support Squad Member
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  3. #23
    Yes, @Jim , pls update us on what the great humanitarian Wise Young is up to with Mononuclear cord blood implantation.

    Consider there was a study done in 2013 using cord blood stem cells (note: not as intensive as below & above injury site implementation of mononuclear cord blood as Wise is doing) had positive results:

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146127/

    In this study, 25 patients with traumatic spinal cord injury (injury time > 6 months) were treated with human umbilical cord blood stem cells via intravenous and intrathecal injection. The follow-up period was 12 months after transplantation. Results found that autonomic nerve functions were restored and the latent period of somatosensory evoked potentials was reduced. There were no severe adverse reactions in patients following stem cell transplantation. These experimental findings suggest that the transplantation of human umbilical cord blood stem cells is a safe and effective treatment for patients with traumatic spinal cord injury.


    The stem cell treatment group comprised 9 females and 16 males, 5 (20%) of which were quadriplegic and 20 (80%) were paraplegic. Through regular and MRI examinations, there were no severe complications, neoplasm or aggravated neurological symptoms shown. Three (12%) patients had fever after infusion of stem cells; their body temperature was maintained at 37?38?C, there were no abnormities in the levels of white blood cells and the fever was retained for less than 24 hours. The fever could be controlled by physical hypothermia. There was no statistically significant difference in terms of complication rates between the paraplegic and the quadriplegic patients (P > 0.05).

    Improvements of neurological function in patients with spinal cord injury after human umbilical cord blood stem cell transplantation (Table 2)

    Table 2

    The amount and percentage of patients [n (%)] with improvements in different functions after human umbilical cord blood stem cell transplantation



    At 12 months after stem cell therapy, 4 patients (16 %) showed improvements in American Spinal Cord Injury Association score: one case was cervical spinal cord injury, two cases were thoracic spinal cord injury, and one case was lumbar spinal cord injury. Spasm decreased in seven patients (28%) after stem cell therapy, including three cases with cervical spinal cord injury and four cases with thoracic spinal cord injury. Eight patients (32%) had improved autonomic function after stem cell therapy, including two cases with cervical spinal cord injury, four cases with thoracic spinal cord injury, and two cases with lumbar spinal cord injury. Six patients (24%) had improved urinary function after stem cell therapy, including one case with cervical spinal cord injury, three cases with thoracic spinal cord injury, and two cases with lumbar spinal cord injury (Table 2, Figure 1). Nine patients (36%) had improved somatosensory evoked potential tests after stem cell therapy, including two cases with cervical spinal cord injury, five cases with thoracic spinal cord injury, and two cases with lumbar spinal cord injury (Table 2).

    We are now in 2018 and this treatment is not available. Which begs the question, why?
    Last edited by Pauly1; 02-24-2018 at 04:03 AM.

  4. #24
    Looks like this treatment may be available within 90 days. As posted here:

    Quote Originally Posted by lunasicc42 View Post
    so where exactly are we in the process of getting scinetusa up and recruiting ... What exact step are we waiting on and Whats next

    Quote Originally Posted by Jim View Post
    When we get the ok from the FDA (within 90 days) I will post instructions how to apply. You will apply directly to the hospital performing the surgery.

  5. #25
    That doesn't make it "available". That just allows them the option to conduct that specific study. Who knows how long it'll take to train, recruit, etc. Still though, it's a step forward. Lots of pun intended.

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