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Thread: First Ever Quadriplegic Treated With Stem Cells Regains Motor Control in His Upper Bo

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    Senior Member KIM's Avatar
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    First Ever Quadriplegic Treated With Stem Cells Regains Motor Control in His Upper Bo


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    Annoying as hell that these marketing articles never give ASIA classification or complete vs. Incomplete.

  3. #3
    http://asteriasbiotherapeutics.com/a...nt-population/

    FREMONT, Calif. – Sept. 27, 2016 – Asterias Biotherapeutics, Inc. (NYSE MKT: AST), a biotechnology company pioneering the field of regenerative medicine, today announced that the first patient with incomplete AIS-B cervical spinal cord injury was successfully dosed with 10 million cells of AST-OPC1 (oligodendrocyte progenitor cells) in the SCiSTAR clinical trial at Shepherd Center in Atlanta. The company recently received FDA clearance to expand the study into this additional patient population based on the continued favorable safety profile observed in the ongoing clinical study. A total of 5-8 AIS-B patients are expected to be enrolled and dosed with 10 million cells in the study. Asterias recently reported positive early efficacy data for AST-OPC1 in AIS-A patients, or those with complete cervical spinal cord injuries.

  4. #4
    http://asteriasbiotherapeutics.com/a...with-ast-opc1/

    FREMONT, Calif. – Sept. 14, 2016 – Asterias Biotherapeutics, Inc. (NYSE MKT: AST), today presented positive interim efficacy data from the 10 million cell cohort in the Company’s ongoing AST-OPC1 SCiSTAR Phase 1/2a multicenter clinical study in complete cervical spinal cord injury patients. While early in the study, with only 4 of the 5 patients in the cohort having reached 90 days after dosing, all patients have shown at least one motor level of improvement so far and the efficacy target of 2 of 5 patients in the cohort achieving two motor levels of improvement on at least one side of their body has already been achieved. Patient improvements are being measured by the ISNCSCI neurological classification scale widely used to quantify functional status of patients with spinal cord injuries. As suggested by existing research, patients with complete cervical spinal cord injuries that show two motor levels of improvement on at least one side may regain the ability to perform daily activities such as feeding, dressing and bathing.

  5. #5
    This was covered in the last few weeks under Asterias. There are some good articles and video of him doing things that was put on the other threads. They will try 20 million cells in the future patients

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    Senior Member lunasicc42's Avatar
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    now we need some good news like this for chronics
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  8. #8
    First ever? Tall claim. The Chinese have been doing it successfully since the late 90's. Here's an account from mid-2000.

    c3-c7 complete SCI treated with umbilical stem cells via surgery and CT-guided fine needle (2005)




    https://www.youtube.com/watch?v=4jIB63T8VrE (same video but without subtitles) has in the description the gains from Stem Cell treatment:

    This patient?s story is edited and made out into a short film, which is published on a TV programme, named ?Approaching science? of CCTV channel and can be watched globally.

    Mr. Dong Chuan, 21 years old, suffered from C6 blow-out fracture via an accident since 2005, then was founded C3-C7 complete spinal cord injury, the body below his neck is palsy, no sensation. His main symptoms included severe spasm of his limbs, central neural high temperature, frequently high fever, his weight is reduced from 70kg to 40kg 1 year after the accident.

    1. Before receiving the stem cell transplantations, we can see that:

    The body below his neck is palsy;
    Severe spasm of his limbs;
    Central neural high temperature, underwent high fever frequently;
    His weight is reduced to 40kg;
    He could not control his urination and bowl movement by himself.

    2. After receiving the stem cell transplantations, the patient is able to:

    His muscle tension is improved to normal level;
    The sensation of his body is improved obviously;
    Feeding himself by holding a spoon in person;
    Playing his computer by himself;
    Sweating by himself;
    Standing by himself via braces;
    His weight is increased to over 70kg;
    Controlling urination and bowl movement by himself.
    Last edited by Pauly1; 10-13-2016 at 10:19 PM.

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