J Alzheimers Dis. 2016 Jul 2;53(3):1209-30.
Moving from the Dish to the Clinical Practice: A Decade of Lessons and Perspectives from the Pre-Clinical and Clinical Stem Cell Studies for Alzheimer's Disease.
Salem H1,2, Rocha NP1, Colpo GD1, Teixeira AL1.
To date, there is no definitive treatment for Alzheimer's disease (AD). The realm of stem cells is very promising in regenerative medicine, particularly neurodegenerative disorders. Various types of stem cells have been used in multiple trials on AD models, trying to find an innovative management of this disease. In this systematic review, we trace the published preclinical and clinical data throughout the last decade, to show how much knowledge we gained so far in this field and the future perspectives of stem cells in AD treatment.
Alzheimer?s disease; clinical trails; neurodegenerative diseases; preclinical trials; stem cells