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Thread: Osteoporosis Treatment

  1. #11
    Senior Member Flatiron's Avatar
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    Quote Originally Posted by SCI-Nurse View Post
    Actually, a number of studies have been done with SCI, showing no scientific evidence of benefit, and sometimes actual harm.

    (KLD)
    Quote Originally Posted by DaDutchman View Post
    Do you know where or how I can access these studies? My primary physician keeps wanting me to take something.

    Thanks

    Same here with my Dr.
    Would be nice to have evidence/facts.

  2. #12
    Senior Member TomRL's Avatar
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    I've been trying to find any articles online, but so far with no luck. I would like to shows som of this material to my endocrinologist as well. Especially since he's of the opinion that it can't do any harm. Sometimes I wonder if he's ever read the warnings on drugs
    Tom

    "Blessed are the pessimists, for they hath made backups." Exasperated 20:12

  3. #13
    Senior Member TomRL's Avatar
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    Tom

    "Blessed are the pessimists, for they hath made backups." Exasperated 20:12

  4. #14
    I've searched for scholarly articles, and haven't had much success in finding definitive information.

    It's frustrating to read sentences like the ones below. I don't understand why an author of a paper like this wouldn't go on to outline the negative side effects or offer educated conjecture as to why these drugs might be unsafe for someone with a spinal cord injury.


    • "Negative side effects after long-term use have been reported recently in studies in the general population."
    • "We don’t know how safe it is for individuals with SCI to use these drugs for the long-term."

    http://sci.washington.edu/info/forum...teoporosis.asp

    All the best,
    GJ

  5. #15
    Senior Member TomRL's Avatar
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    I saved this from a previous post by someone, but I don't remember who posted. I should have been searching my computer instead of the internet.

    Actually, there are not great studies showing that bisphosphonates are effective in either prevention or treatment of osteoporosis in people with SCI. These drugs also are not benign, and come with the possibility of some fairly significant side effects. Also, we have virtually no published research about the effects of menopause on women with SCI, either related to osteoporosis or otherwise.

    There is a significant problem with many of the studies because of the bone areas that were included in DEXA scanning. We know that the osteoporosis is worst in most people with SCI in the following areas: distal femur, proximal tibia, and proximal femur. It can also occur in the humerus in those with tetraplegia. Lumbar spine osteoporosis is relatively rare in people with SCI, unlike in post-menopausal AB women. Most DEXA scanners are only programmed to measure bone density in the wrist, lumbar spine, and femoral neck, so unless special software is obtained for the scanner to include the ability to analyze the SCI areas at more risk, the effectiveness of therapies may be misinterpreted.

    Passive standing (ie, in a standing frame) has not been shown to be effective in either prevention or treatment. Vibrating plate therapy while standing holds some promise, as does FES.

    Here are a few recent articles about osteoporosis in SCI.

    http://journals.plos.org/plosone/art...l.pone.0081124

    http://link.springer.com/article/10....914-012-0117-0

    http://www.sciencedirect.com/science...03999314008909

    http://www.sciencedirect.com/science...03999315014835

    http://link.springer.com/article/10....198-015-3326-4

    http://www.sciencedirect.com/science...34148214013586

    http://link.springer.com/article/10....2557-5#/page-1

    http://link.springer.com/article/10....1879-4#/page-1

    http://link.springer.com/article/10....0602-x#/page-1

    http://www.rehab.research.va.gov/jou...01/page17.html

    http://www.aginganddisease.org/EN/ab...ct147370.shtml

    http://www.tandfonline.com/doi/full/...14Y.0000000200


    Here is a Cochrane Review of non-drug therapy interventions:

    http://onlinelibrary.wiley.com/doi/1....CD010620/full
    Tom

    "Blessed are the pessimists, for they hath made backups." Exasperated 20:12

  6. #16
    Senior Member CapnGimp's Avatar
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    Exclamation

    Quote Originally Posted by SCI-Nurse View Post
    Actually, a number of studies have been done with SCI, showing no scientific evidence of benefit, and sometimes actual harm.

    (KLD)
    CORRECT! Never take meds for osteo, drs push pills with no concern for the MULTITUDE of harmful side effects. If you learn ANYTHING from CC, it should be the overwhelming preponderance of evidence pointing to the reality of DRs are pill pushers. There will be well meaning people on here that just haven't accepted reality YET and will agree with "a pill or two will solve your problems". Scientific studies my aRse, educate yourself. "Papers' and 'scientific articles' submitted to 'peer review and approved' then published... laymen's terms?? Voodoo practitioners helping one another get grants, get rich and keep jobs<__Reality.

  7. #17
    Senior Member Flatiron's Avatar
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    Just so every body would know, I decided not to take any prescribed medications.

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