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Thread: Stemcellsinc is out ?!

  1. #11
    I'm surprised they lasted as long as they did. I'd be pissed if I were an investor.

  2. #12
    Quote Originally Posted by Nowhere Man View Post
    I'm surprised they lasted as long as they did. I'd be pissed if I were an investor.

    Companies showing no profits and no income don't have investors, they have speculators. There is a difference and they know the risk.
    please . . .test what you already know; and give us what you have. we may not be dying, but we certainly are not living either

  3. #13
    Quote Originally Posted by Nicksdad View Post
    Companies showing no profits and no income don't have investors, they have speculators. There is a difference and they know the risk.
    Granted, I have not followed this trial closely, but I don't remember Stemcells Inc. calling the interim data "disappointing". I thought they were excited about their interim results. Now all of a sudden, their results are "extremely disappointing" & they're winding down operations. All in one day? All I'm saying is that I'd be pissed if I were an investor. I'm sure this happens all the time in the stock market.

  4. #14
    Quote Originally Posted by Nicksdad View Post
    Companies showing no profits and no income don't have investors, they have speculators. There is a difference and they know the risk.
    LOL. You get it.
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  5. #15
    Senior Member lunasicc42's Avatar
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    Quote Originally Posted by Nowhere Man View Post
    Granted, I have not followed this trial closely, but I don't remember Stemcells Inc. calling the interim data "disappointing". I thought they were excited about their interim results. Now all of a sudden, their results are "extremely disappointing" & they're winding down operations. All in one day? All I'm saying is that I'd be pissed if I were an investor. I'm sure this happens all the time in the stock market.

    I thought the exact same thing .....about them saying that they were excited about their interim results in a newsletter not too long ago...now the total opposite?
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  6. #16
    Quote Originally Posted by lunasicc42 View Post
    I thought the exact same thing .....about them saying that they were excited about their interim results in a newsletter not too long ago...now the total opposite?
    I was never impressed with the interim results nor the pre-clinical animal studies (were very weak in my opinion). I couldn't believe they ever initiated this trial. But I live SCI and have been on this board for years. Those investors probably know jack sh*t about SCI, which made it a dangerous investment for them. They probably had nothing to go by except word from management.

  7. #17
    This U. of Miami Hospital article was published in April, prior to the May 31 StemCells Inc. announcement.


    http://ummd.med.miami.edu/news/2016/...d-injury-after


    Motor Improvement Seen in Patients with Cervical Spinal Cord Injury After Stem Cell Implantation

    ALLAN D. LEVI, M.D.

    Spinal cord injured patients in the StemCells, Inc. trial being conducted at University of Miami Hospital are demonstrating improvements in both hand strength and function. They are the first cohort in the Phase II pathway study, Allan D. Levi, M.D., Ph.D., professor and chair of the Department of Neurological Surgery and staff scientist at The Miami Project to Cure Paralysis, is one of the lead sites. The study is designed to measure the effects of implanting stem cells in patients with cervical spinal cord injury (SCI). The assessment of motor function involved using tests of dexterity and grip.
    Levi was the first investigator to perform a stem cell transplant into the chronically injured cervical spinal cord of a patient. This first cohort of the study was designed to assess the safety and preliminary signs of efficacy of cell administration into the cervical spinal cord and help determine the dose level for the 40-patient second cohort — a randomized, controlled, and single-blinded arm of the trial, which is already underway.
    “The safety of the procedure with increasing doses of stem cells is one of the first important observations of this trial,” said Levi.
    The patients in the study were selected because they had complete loss of motor control below the level of injury, the most severe degree of SCI as defined by the American Spinal Injury Association Impairment Scale. Clinicians used both International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI) and Graded Redefined Assessment of Strength, Sensibility and Prehension (GRASSP) measures to establish a pre-transplant baseline for each patient, and to assess post-transplant progress.
    Based on the six-month follow-up for the first cohort, an overall pattern of motor improvement was detected in four of the six patients as measured by gains in both strength and function on the collective ISNCSCI and GRASSP outcomes.
    “Any improvement in motor function is incredibly important to this patient population, and as a researcher and clinician is very exciting to observe,” said Levi.


    Additional highlights of the interim results include improved muscle strength in five of the six patients, with four of the five patients having gains in muscle strength and also demonstrating improved performance in functional tasks assessing dexterity and fine motor skills. Four of the six patients had improvement in the spinal level of injury as defined by the ISNCSCI assessment; three upgraded one level and one upgraded two levels. Additionally, changes in muscle strength and function were observed around three months post-transplant, consistent with the onset of sensory improvements seen in the company’s initial Phase I/II thoracic study, and no adverse events were attributed to the cells.

    “The emerging data are the first clinical evidence of a treatment improving muscle strength and function following cellular transplant in spinal cord injuries,” said Armin Curt, M.D., the principal investigator at the University of Zurich, Switzerland, for the company’s previous Phase I/II thoracic spinal cord injury study. “These findings are even more compelling given that all the patients are between one and two years post-injury.”
    To refer a patient to a UHealth Neurosurgeon call (305) 243-UMMD (8663).



  8. #18
    Super Moderator Sue Pendleton's Avatar
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    Damn. According to the most recent New Mobility they are still recruiting quads for a phase 2 since the safety was established. At my age I was still looking at all the info but basically had decided to give this one a go.

    As far as keeping such companies going, well, first they need enough from VC and angels to get them to where they can be listed. Then, the best and safest way to invest in these companies is an ETF of biotechs. A good investment ETF would be heavy on more established companies like Celgene, Pfizer and Acorda then have a bit of several smaller companies like StemCell Inc, NeuralStem, etc. ETFs are like mutual funds but often specialize in one area of the economy or a group of companies in a country or a group of companies from a group of countries like the former WARSAW Pact.
    Courage doesn't always roar. Sometimes courage is the quiet voice at the end of the day saying, "I will try again tomorrow."

    Disclaimer: Answers, suggestions, and/or comments do not constitute medical advice expressed or implied and are based solely on my experiences as a SCI patient. Please consult your attending physician for medical advise and treatment. In the event of a medical emergency please call 911.

  9. #19
    Stem cells inc is still recruiting?

  10. #20
    https://clinicaltrials.gov/ct2/show/...+injury&rank=4

    Quote Originally Posted by legitsrs View Post
    Stem cells inc is still recruiting?

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