Not sure which came first, but I seem to be stuck in a horrible pattern now. I have been stressed out for about 6-8 months with my own degenerative disability and my able bodied husband going through some scarey medical stuff of his own. He seems to be getting to the other side of his stuff while I am stuck in anxiety mode and it is destroying my sleep. I have had to have prescription meds for sleep for the last 20 or so years. For the last decade a cocktail of 100 mg Trazodone, 10 mg Ambien, and 3 mg of Melatonin worked like a charm. Now it seems to have quit me, I had my doctor switch me to Lunesta and it doesn't seem to be working either. I took 1/2 of a Valium the last few nights which helps me initially fall asleep but I still wake up after a few hours. Now I can't even tell if I am exhausted, anxious, depressed, despondent.....etc. I am so messed up. I take 100 mg of Zoloft in the mornings, and have been on it 20 years. I am wondering if it has quit me too?