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Thread: StemCells, Inc. Announces Webcast to Discuss Interim Results

  1. #11
    Senior Member Tbone57's Avatar
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    thats impressive

  2. #12
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    Thanks Kate

    My left hand barely can do this, but my right hand cannot.

    Your thoughts on the slow migration over time that would improve the lower extremities?

  3. #13
    Moderator kate's Avatar
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    I don't understand the physiology well enough to answer the slow progression . . . MAYBE an eventual treatment would involve a pair of injections? The original safety studies were done with thoracic injuries, very low doses. Those people got some sensation but no motor return.

    If anybody cares, I wrote about the science behind this work in the Working 2 Walk 2012 book. The chapter about it is posted here.

    In the new book it's in Chapter 10 (Visitors from Another Galaxy).

  4. #14
    Impressive. I imagine there's some sensory improvement too

  5. #15
    Senior Member PC720's Avatar
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    Quote Originally Posted by spayne View Post
    Thanks Kate

    My left hand barely can do this, but my right hand cannot.

    Your thoughts on the slow migration over time that would improve the lower extremities?
    My understanding is that the cells do not stay in the initial injection site but rather migrate throughout the spinal cord over time. In some of the other testing that I've read about involving animals, cells have even made it as far as the optic nerves depending on the injection site. The cells don't just survive but proliferate.


    Somebody feel free to correct or elaborate

    As far as lower extremities go, I would imagine that would come along as well; however, I would imagine locomotion is yet another task the brain would have to relearn. I don't know about this video because I did not watch it, but the width of the spinal cord can affect strength and ability.


    "a with of 9mm can make all the difference to somebody who is a quadriplegic. It is the difference between being able to use the hands or not. Being able to make that connection is our first priority"

  6. #16
    Why is it that they don't expect any spontaneous improvment in InJuries over 12 months old? I thought after three months the damage was done. Do they assume that their cell are not affective enough to awaken even a few atrophied axons further then 12 months

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