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Thread: Adenosine receptors and chronic neuropathic pain

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    Adenosine receptors and chronic neuropathic pain

    Animal study from NIH and St. Louis University making the news. Will hopefully lead to new drug development.

    "Activating the A3 receptor either by its native chemical stimulator, the small molecule adenosine, or by powerful synthetic small molecule drugs invented at the NIH prevents or reverses pain that develops slowly from nerve damage without causing analgesic tolerance or intrinsic reward (unlike opioids)."

    http://www.slu.edu/x98903.xml

    The full article:
    http://brain.oxfordjournals.org/cont...wu330.full.pdf

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