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Thread: StemCells, Inc. Provides Update on Its Phase I/II Study in Spinal Cord Injury

  1. #1

    StemCells, Inc. Provides Update on Its Phase I/II Study in Spinal Cord Injury

    Significant Sensory Gains Observed in Additional
    Patients


    NEWARK,
    Calif., May 19, 2014 (GLOBE NEWSWIRE) -- StemCells, Inc. (Nasdaq:STEM)
    announced today that
    Armin Curt, M.D., study principal
    investigator, presented an interim update on the Phase I/II trial in spinal cord
    injury at the Annual Meeting of the American Spinal Injury
    Association in San
    Antonio, Texas. Interim analysis of clinical data to date has shown
    that the significant post-transplant gains in sensory function first reported in
    two patients have now been observed in two additional patients.

    http://investor.stemcellsinc.com/pho...2195&highlight=

  2. #2
    And there is a presentation included which illustrates the gains:

    http://www.stemcellsinc.com/Presenta...ASIA_FINAL.pdf

  3. #3
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    Quote Originally Posted by Proteus View Post
    And there is a presentation included which illustrates the gains:

    http://www.stemcellsinc.com/Presenta...ASIA_FINAL.pdf
    this is a great summary. excellent results, truly we are seeing the beginning.

    actual sensory gains!

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    Senior Member muskie's Avatar
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    I hope the can find a way to couple this with motor gains as well. Would have liked to see a higher percentage of folks getting returns perhaps the cell dosage may have been to low for them. Still exciting news
    Last edited by muskie; 05-20-2014 at 10:32 AM.
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    Senior Member lunasicc42's Avatar
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    Quote Originally Posted by muskie View Post
    I hope the can find a way to couple this with motor gains as well. Would have liked to see a higher percentage of folks getting returns perhaps the cell dosage may have been to low for them. Still exciting news
    So would it be logical to next couple this type of therapy with locomotor training ?
    "That's not smog! It's SMUG!! " - randy marsh, southpark

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    Locomotor with E-Stim?

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    Senior Member muskie's Avatar
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    maybe, I am far from an expert. I just see that there is positive results from a few different groups and to me maybe just maybe this is the beginning to get you folks and my son out of those damn chairs and reclaim what was stolen from you
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    Senior Member lunasicc42's Avatar
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    Quote Originally Posted by muskie View Post
    maybe, I am far from an expert. I just see that there is positive results from a few different groups and to me maybe just maybe this is the beginning to get you folks and my son out of those damn chairs and reclaim what was stolen from you
    Thanks for the nice sentiment...fingers crossed
    "That's not smog! It's SMUG!! " - randy marsh, southpark

    "what???? , you don't 'all' wear a poop sac?.... DAMNIT BONNIE, YOU LIED TO ME ABOUT THE POOP SAC!!!! "


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  9. #9
    Quote Originally Posted by muskie View Post
    I hope the can find a way to couple this with motor gains as well. Would have liked to see a higher percentage of folks getting returns perhaps the cell dosage may have been to low for them. Still exciting news
    I have red somwhere they are planning to double the dosage of cells in the next thoracic patients. That should show more recovery.

    I wonder why they didn't include yet also ASIA C patients as it was planned. The animal studies showed motor recovery in rats with some mobility like ASIA C patients.

    In any case I don't expect stem cells alone to provide much more recovery that this. They need to add something else like Chase, growth fators etc.. to see better results IMO. I know they know, but I don't know if they are working on it in the labs or if are just planning to team up with others working on complementary lines of reseach.

    Paolo
    In God we trust; all others bring data. - Edwards Deming

  10. #10
    Quote Originally Posted by paolocipolla View Post
    I have red somwhere they are planning to double the dosage of cells in the next thoracic patients. That should show more recovery.

    I wonder why they didn't include yet also ASIA C patients as it was planned. The animal studies showed motor recovery in rats with some mobility like ASIA C patients.

    In any case I don't expect stem cells alone to provide much more recovery that this. They need to add something else like Chase, growth fators etc.. to see better results IMO. I know they know, but I don't know if they are working on it in the labs or if are just planning to team up with others working on complementary lines of reseach.

    Paolo
    One slow step at a time. I'm more interested in the Phase II results when they come out.
    Last edited by Skipow; 05-21-2014 at 04:27 PM.

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