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Thread: Large animal trial for Chondroitinase is underway

  1. #31

  2. #32

    more info re dates/ dog trial


  3. #33
    It was listed as a 3 year trial and started in July 2013. I believe they were hoping to treat around 20 per year. So far they've treated 15. Hopefully recruitment stays at a brisk pace so they finish the trial with as close to 60 as possible. They have about 45 to go.

  4. #34
    The trial is going well. A 2014 thank you video from the Iowa State University College of Vet Medicine. LINK:

  5. #35
    Senior Member ian's Avatar
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    great. When do the human trials start.

  6. #36
    Quote Originally Posted by ian View Post
    great. When do the human trials start.
    They do not even have the results and data from the large animal (dog) trial yet. We'll be able to find out more when the dog trial has actually finished and the data gets analyzed. They're in the middle of the trial right now.

  7. #37
    Senior Member ian's Avatar
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    Im being sarcastic. Chondroitinase has been around for quite a while. Dog trials are worthless to the SCI community. Its hope, but its false hope.

  8. #38
    Senior Member tarheelandy's Avatar
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    Never having seen a paralyzed dog I have to wonder, do their owners have to use catheters on their dog?

  9. #39
    Senior Member ian's Avatar
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    Peter Fry who has passed away used to tell me the story of a SCI dog he knew of who the owners used to cath all the time.

  10. #40
    Quote Originally Posted by ian View Post
    Im being sarcastic. Chondroitinase has been around for quite a while. Dog trials are worthless to the SCI community. Its hope, but its false hope.
    On top of being able to tell us something about walking and motor function, dogs can be trained when and where they are allowed to go to the bathroom, which makes learning about bowel and bladder function much easier. Additionally, these are all dogs with "real world" spinal cord injuries, rather than ones perfectly created in a lab, so this trial will tell us what affect ch'ase has on those types of injuries. Lastly, it will give us insight into whether or not ch'ase plus rehabilitation can be effective in mammals larger than rats. If this trial shows no efficacy for anything, it lets us know that ch'ase may not be worth pursuing any further (at least as it was used in this trial.) If this trial shows positive results, it will greatly accelerate the pace at which human trials may begin.

    This trial is probably one of the most important animal trials to date.

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