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Thread: Long term acetaminophen use

  1. #1

    Long term acetaminophen use

    I've been using Norco for several years now which has 325mg acetaminophen per pill. I don't take a very high does but I use it pretty frequently, 1-2 pills per day. Does anyone know if there is any risk from long term acetaminophen use even if I stay well under the daily max dose?

  2. #2
    Senior Member
    Join Date
    May 2006
    Somewhere in the Rocky Mountains
    The doctor who prescribed it should probably check your liver function. Long term use can sometimes do liver harm. But it is a low dose so you are probably fine. Most doctors try to avoid using acetaminophen long term.

  3. #3
    Super Moderator Sue Pendleton's Avatar
    Join Date
    Jul 2001
    Wisconsin USA
    I agree with DD. I can't take NSAIDs normally due to acid reflux and a history of bleeding ulcers in women in my family. But when I get blood work done annually I make sure liver function tests are a part of it. One of my former primary care docs did say not to take Tylenol PM on a regular basis. I think this had more to do with how most react to taking antihistamines long term than the acetaminophen in it. I believe max dose for those who aren't heavy drinkers is 3,000 milligrams a day of acetaminophen and I never come close to that amount.

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