My doctor is prescribing Cymbalta for pain and is talking about trying Zanaflex and Dantrolene.

Does anyone have experience with these, especially the downsides and how hard it is to get off them?

And doseages you've ended up on etc.

I've tried Gabapentin and lyrica, which both worked initially, but then I had to increase the doseage to keep the effect, and of course the side effects increased by the same factor with each doseage increase. Getting off lyrica was to put it bluntly a F#$#ing bitch. Don't want to go through that again with another drug.


Cymbalta
Duloxetine (sold under the brand names Cymbalta, Ariclaim, Xeristar, Yentreve, Duzela)
http://en.wikipedia.org/wiki/Duloxetine

Zanaflex
Tizanidine (trade names Zanaflex, Sirdalud)
http://en.wikipedia.org/wiki/Tizanidine

Dantrolene
Dantrolene sodium
http://en.wikipedia.org/wiki/Dantrolene