Results 1 to 3 of 3

Thread: Clinical trial start June 2004!

  1. #1
    Senior Member
    Join Date
    Mar 2002
    Location
    Houston,Tx
    Posts
    579

    Clinical trial start June 2004!

    Gene therapy grants further national initiative
    Alan Tucker, lab supervisor at TulaneÂ’s Center for Gene Therapy, is operating a flow cytometer in order to sort stem cells. The center is now one of the main distributors of adult stem cells throughout the world.

    Alan Tucker, lab supervisor at TulaneÂ’s Center for Gene Therapy, is operating a flow cytometer in order to sort stem cells. The center is now one of the main distributors of adult stem cells throughout the world.
    Lynn Rice



    Lynn Rice
    staff writer

    August 29, 2003-- This past summer, the Tulane University Center for Gene Therapy received two grants totaling over $3 million to develop various stem cell research projects.

    This funding, from the National Institute of Health, comes in the face of an expanding body of knowledge on both stem cells and their evident potential to repair damaged tissues.

    Ultimately, if laboratory protocols are refined, it appears stem cell therapy could become an effective treatment for a vast array of terminal conditions such as chronic heart disease, Alzheimer's, Parkinson's and liver, kidney and lung diseases.

    While stem cells were found over 100 years ago, research on tissue reparation is relatively new. Investigation into this area has only occurred in the past 20 years. Therefore, scientists still do not have a clear understanding of which stem cells relate to which disease, making centers such as Tulane's necessary.

    Tulane's Center for Gene Therapy was established in July 2000. It was initially run by Dr. Darwin Prockop and a group of 14 others.

    Two major projects are now being conducted under the recent grants given by NIH. The first is an initiative that prepares stem cells for multiple research purposes. Prockop and a team of Tulane University graduate students are setting up a stem cell distribution center where they will send out standardized stem cells to various national and international affiliate scientists. The distribution center will offer adult human and rat stem cells.

    The second project is being conducted in affiliation with William Chilean, a co-principal investigator at LSU Health Sciences Center. This project works to better characterize heart disease by developing models for the condition using stem cells from the patients' own bone marrow. As a part of this project, the researchers will also induce heart attacks in rats by tying off their coronary arteries and then inject stem cells into the rats' systems to examine the effect. These experimental trials will provide insight to see if stem cell therapy could be valuable to patients with heart conditions.

    Prockoff was hesitant to make any presumptions about where the research might lead. He did acknowledge that stem cells have a remarkable capacity to rebuild tissues by targeting damaged cells, and this capacity could be cultivated to treat patients with damaged tissues whose bodies simply cannot repair the damages quickly enough.

    Therapy for a patient would consist of taking a sample of a patient's bone marrow and using it to make more of the patient's own stem cells. "The form of stem cell therapy we are interested in is merely accelerating the body's natural healing process," Prockop said.

    Prockop's group is currently planning a clinical trial to treat patients with spinal cord injuries. It is scheduled to take place in June of 2004.

    As for the long-term future goals of the center, Prockop said, "We wish to cure the diseases."

  2. #2
    Senior Member Schmeky's Avatar
    Join Date
    Sep 2002
    Location
    West Monroe, LA, USA
    Posts
    3,412
    This has been delayed and will not begin until "sometime" in 2005.

    As previously stated, it is targeted (at least initially) for acute SCI. However, this will be a well funded, high tech, world class trial with global affiliates.

  3. #3
    Senior Member
    Join Date
    Mar 2002
    Location
    Houston,Tx
    Posts
    579
    need more detail..

    [This message was edited by Superstar on 06-07-04 at 12:27 AM.]

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
  •