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Thread: $100 million OKd for stem cell research

  1. #1

    $100 million OKd for stem cell research

    I think they are going to give the money. Hope they use it in good health.


    $100 million OKd for stem cell research
    HEALTH $100 million OKd for research on debilitating or fatal diseases
    Erin Allday
    Updated 10:35 p.m., Thursday, July 26, 2012


    California's stem cell funding agency on Thursday approved nearly $100 million in grants for research into heart disease, cancer and spinal cord injuries, and to the cheers of dozens of patients and their supporters, it also awarded money to rare but devastating diseases with no cure.


    read article:

    http://www.sfgate.com/health/article...ch-3739274.php

  2. #2
    From the article.......

    SCI related.........

    Scientists at StemCells Inc. in Newark were awarded $20 million for a spinal cord study.


    The StemCells Inc. grant will go toward transplanting neural stem cells into patients with neck, or cervical spinal cord injuries. StemCells Inc. already has studied similar procedures in patients with thoracic spinal cord injuries, but injuries to the neck are more common.

    And for embryonic stem cells (non-SCI)........

    Stanford's heart disease grant will go to a project that involves implanting embryonic stem cells that are programmed to become heart cells into sections of the heart that have died. The study is looking only at patients who are in end-stage heart failure, meaning they need a heart transplant to survive. Because hearts for transplantation are so hard to come by, doctors have long sought a treatment that can repair dead heart*tissue.

    "The exciting part about this funding is it will allow us to be the first group in the world to implant human embryonic stem cells into a human heart," said Dr. Robert Robbins, director of the Stanford Cardiovascular Institute.

    "We know we can get beating cardiac cells from embryonic stem cells. The trick is going to be getting those to incorporate into the myocardium, to survive, and then to coordinate with the normal muscle of the heart," Robbins said. "That is not a trivial*thing."

  3. #3
    this is great! my neck is ready for action.



    Stem cells for neck injury: $20 million
    July 27th, 2012, 3:45 pm · · posted by Pat Brennan, science, environment editor


    The state’s stem-cell institute has awarded $20 million to UC Irvine researchers, along with a private company, to prepare the way for human testing of a treatment for spinal-cord injuries in the neck region — one that could restore movement and independence for some of the 1.3 million spinal-cord injury sufferers in the United States.

    The treatment, developed by the husband and wife research team, Aileen Anderson and Brian Cummings, along with StemCells Inc. of Newark, Ca., would involve injecting versatile human neural stem cells into the neck area.

    The cells, capable of transforming themselves based on cues from the body, could then migrate to the injured area and perhaps repair the protective sheaths, known as myelin, around nerve cells. If the treatment works as expected, it would restore movement and body control for patients with debilitating injuries.

    read...

    http://sciencedude.ocregister.com/20...illion/174507/

  4. #4
    Quote Originally Posted by manouli View Post
    The cells, capable of transforming themselves based on cues from the body, could then migrate to the injured area and perhaps repair the protective sheaths, known as myelin, around nerve cells. If the treatment works as expected, it would restore movement and body control for patients with debilitating injuries.
    http://sciencedude.ocregister.com/20...illion/174507/
    Dr.Silver, there is such an opinion among very competent and versed in neurology top spesialists, that embedding of stem sells (no matter wich type of them) is PRINCIPALLY can not have any regenerative potential in case of damage to spinal cord. Thus, once again, what we are talking here about,-regeneration or restoration and plasticity?

  5. #5
    Quote Originally Posted by jsilver View Post
    After so many years of hype and unfounded promises of "within 5 years" I can imagine the frustration. So we have now entered a period of stem cell feeding frenzy with clinical trails popping up everywhere. I have great hope that stem cells will offer benefit at acute stages. They have powerful neuroprotective effects, but I see nothing credible (except maybe for Anderson/Cummings, Stem Cells INC, I think) of their effect at chronic time points after SCI.
    " ... At the histological analysis of their dissected spinal cord, no MSCs were found within the host ..."
    " ... In conclusion, we bring here some new evidences that MSCs most likely act throughout their secretions and not via their own integration/differentiation within the host tissue." (Mesenchymal Stem Cell Graft Improves Recovery after Spinal Cord Injury in Adult Rats through Neurotrophic and Pro-Angiogenic Actions.(http://www.ncbi.nlm.nih.gov/pubmed/22745769) thanks, wildwilly, for providing this).
    Dr.Silver, the answer to my question above seems obvious, but it nevertheless would be nice just to hear what you may add here.

  6. #6
    The aim of this study was to graft MSCs by intravenous injection "one week" after a spinal cord compression injury, in order to assess their effect on functional recovery and find by which mechanisms these cells exert their beneficial effect.

  7. #7
    Yes, GRAMMY, and ...?

  8. #8

    Wink

    Please, use the money wisely.



    CIRM awards $151 million to push stem cell treatments toward trials
    San Francisco Business Times by Ron Leuty, Reporter
    Date: Friday, July 27, 2012, 11:17am PDT - Last Modified: Monday, July 30, 2012, 12:15pm PDT



    Ron Leuty
    Reporter- San Francisco Business Times

    quote:
    Only one of the seven so-called "disease team" awards from the California Institute for Regenerative Medicine, or CIRM, went to industry. That was a $20 million grant for Newark-based Stem Cells Inc. for a spinal cord injury treatment.


    more....

    http://www.bizjournals.com/sanfranci....html?page=all

  9. #9
    Dr.Silver, you know, with a smart intelligent person (this is of course about you) even being for a while silent is a great pleasure, thanks for allowing that, and, of course, my kind regards to our beloved Old Rat.

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