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Thread: Stem Cells Offer Hope to Heart Attack Victims/Israel develops heart tissue from stem cells

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    Senior Member Max's Avatar
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    Stem Cells Offer Hope to Heart Attack Victims/Israel develops heart tissue from stem cells

    Stem Cells Offer Hope to Heart Attack Victims
    Fri Jan 3,10:47 AM ET Add Health - Reuters to My Yahoo!



    LONDON (Reuters) - Stem cells may help patients recover from heart attacks by triggering new cell growth in damaged tissue, scientists said on Friday.



    Stem cells are so-called master cells that can develop into various tissues in the body and using them to repair damaged hearts is a hot area of medical research.


    Two teams of doctors from Germany and Hong Kong reported promising results after transplanting stem cells extracted from bone marrow into heart muscle, although they said more research was needed on the procedure.


    The aim of the procedure is to stimulate blood vessel growth in areas without sufficient blood supply, a process known as angiogenesis. It could eventually offer hope to patients with serious coronary heart disease and those unable to undergo bypass surgery.


    Professor Gustav Steinhoff and colleagues from the University of Rostock, Germany, injected stem cells into six patients' hearts and found five had strikingly improved blood flow, suggesting the cells may have generated growth in damaged areas.


    All patients, however, also underwent conventional bypass surgery. Steinhoff wrote in The Lancet medical journal that further clinical studies were needed to clarify the role of stem cells in the regeneration process.


    A second group of scientists led by Hung-Fat Tse from the University of Hong Kong treated eight patients with stem cells from their own bone marrow and also observed an improvement in blood flow to the heart.


    Last April, Australian surgeons carried out the world's first trial using bone-marrow stem cells to repair heart damage in a 74-year-old man.


    Researchers hope to use stem cells to treat a variety of illnesses, including heart disease, brain disorders and diabetes.


    The work is controversial because of the ethical issues surrounding the use of embryonic and fetal cells. Using adult stem cells culled from bone marrow solves that dilemma--as well as potential problems with tissue rejection. However, adult cells are thought to be less versatile and have fewer potential applications than cells derived from embryos.



    http://story.news.yahoo.com/news?tmp...rt_stemcell_dc

    [This message was edited by Max on Jan 03, 2003 at 03:28 PM.]

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    Senior Member Max's Avatar
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    Israel develops heart tissue from stem cells

    Israel develops heart tissue from stem cells

    Jerusalem, Jan. 3. (UNI): In a major breakthrough, Israeli scientists from Haifa's Technion and Rambam Hospital have developed heart tissue from embryonic stem cells.

    Last year, the scientists there developed human heart cells and now they have produced a heart tissue that beats on the lines of electronic pulses, the Israel Radio has reported.

    The discovery will aid future tissue transplants for heart patients and testing of possible side effects of various medications before they are released in the market.

    Dr Lior Epstein, heading the research team at the Technion's Rappoport Institute, said, "Following the trial tests, the heart tissue appears to be beating like a normal human heart."

    "This tissue may serve as a model on which it will be possible to test how medicines affect the heart," Epstein said.



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