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Thread: Researchers Find Brain Cells Die Differently in Males and Females

  1. #1
    Senior Member Max's Avatar
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    Researchers Find Brain Cells Die Differently in Males and Females

    Researchers Find Brain Cells Die Differently in Males and Females
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    BRAIN CELLS, GLUTATHIONE
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    Researchers at Children's Hospital of Pittsburgh have found that males and females respond differently to brain injury and therefore, boys with brain injuries may require different life-saving treatments than girls.



    Newswise - Researchers at Children's Hospital of Pittsburgh have found that males and females respond differently to brain injury and therefore, boys with brain injuries may require different life-saving treatments than girls.

    Children's researchers found in animal models that levels of glutathione - a molecule that protects brain cells from death when deprived of oxygen - remain constant in females who have suffered an injury to the brain but drop by as much as 80 percent in males with the same injury. When glutathione levels drop, brain cells die much more quickly.

    Results of the study are being presented at the annual Pediatric Academic Societies meeting, held May 1-4, 2004, in San Francisco. This is the second year of five-year, $1.2 million study which is being funded by the National Institutes of Health and Children's Hospital.

    "There is a built-in difference at the brain cell level between males and females, said Robert Clark, MD, an intensivist at Children's Hospital and the principal investigator of the study. "Injured brain cells may eventually die, but they take different pathways to get there in males and females. This means that we may need to develop or use gender-specific therapies for brain injury from any cause."

    http://www.newswise.com/articles/view/504290/

  2. #2
    Banned Faye's Avatar
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    Thanks Max, very interesting!!

    Glutathion levels ( which protect the brain) drop 80% in males when injured, but remain constant in females.

    "Together we stand, divided we fall..."


  3. #3
    I wouldn't doubt it if estrogen was the cause for this.

    -Steven
    ...I like pleasure spiked with pain and music is my aero-plane

  4. #4
    Same here Steve except I was thinking more along the lines of progesterone but unless it exerts a regulating affect on glutathione it wouldn't be a factor.

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