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Thread: Gel 'is helping wounds heal in half the time'

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    Gel 'is helping wounds heal in half the time'

    Gel 'is helping wounds heal in half the time'
    By Celia Hall, Medical Editor
    (Filed: 20/10/2003)


    A new kind of gel that can halve the time it takes for wounds to heal has been developed by scientists.

    The team says that laboratory tests with animals show that an ordinary cut that would normally take about a week to close will heal in three days.

    The gel has wide implications for patients and for the NHS, saving elderly people whose wounds will not heal from the threat of amputation, with many potential savings for the health service.

    Dr David Becker of the department of anatomy and developmental biology at University College, London, who led the team, said: "An estimated 95 million people worldwide suffer from wounds each year and yet few effective wound healing treatments have been developed. There is a large unmet need.

    "This could be used in cosmetic surgery and stop people losing limbs, which is a growing problem because of increasing numbers of elderly diabetic patients with leg ulcers."

    Experiments so far have shown that the gel is effective with the skin, brain tissue, the cornea in the eye and even with injury to the spinal cord where it is possible that it might limit spinal cord damage following an injury.

    The patented product called Nexagon works at a biological level on body cells, accelerating the complex system by which cells organise themselves in order to grow across and close a wound.

    The treatment targets a biological system known as the "gap junction" by which cells on the perimeter of a wounds form tiny pipes or channels through which they communicate and pass material.

    Dr Becker said: "Cells have to talk to each other in order to grow new skin and organise themselves at the edges of a wound to move together and to meet. We are able to speed up these natural processes."

    The scientists believe that Nexagon could be an important treatment for leg ulcers in elderly diabetic patients that will not heal.

    In addition to its healing properties, the gel reduces inflammation at the site of the wound, decreases scarring and, because the wound heals faster, reduces the risk of infection.

    Dr Becker added: "The challenge now lies in taking Nexagon treatment into the clinic.

    "We also wish to investigate new areas of research into wound healing and skin disorders such as psoriasis, using this technology to create the next generation of innovative products."

    They are now seeking a research partner to fund human trials with Nexagon.

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    http://www.telegraph.co.uk/news/main...20/ixhome.html

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    nexagon

    ''Experiments so far have shown that the gel is effective with the skin, brain tissue, the cornea in the eye and even with injury to the spinal cord where it is possible that it might limit spinal cord damage following an injury.''

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    Wound Gel Halves Healing Time

    Wound Gel Halves Healing Time
    Betterhumans Staff
    Tuesday, November 04, 2003, 4:51:23 PM CT




    A bioactive gel that can halve the time it takes for wounds to heal has won a prestigious medical innovation award.

    "An estimated 95 million people worldwide suffering wounds each year, and yet few effective wound healing treatments have been developed, so there remains a large unmet need," says David Becker of University College London.

    Becker led the creation of the gel, called Nexagon, which works by speeding wound closure and reducing inflammation.

    Closing the gap

    Nexagon manipulates a target in wound healing called the gap junction, which is a small channel that allows cells to communicate directly with their neighbors.

    In several experimental models, the gel has spurred wounds to close twice as fast as normal. An everyday cut, for example, heals in three days instead of seven.

    Becker and colleagues say that the gel could have many applications, such as in cosmetic surgery, chronic wound treatment and possibly in reducing damage following spinal cord injury.

    Treating skin disorders

    For its potential, the gel won the Best Biotechnology Start-Up Innovation award at the Medical Futures Innovation Awards in London.

    The researchers are currently seeking an investment partner to fund clinical trials, and aim to research the gel's impact on such skin disorders as psoriasis and keloid scars.

    "I would like to see this product go through to clinical development so that patients can take advantage of this revolutionary technology as soon as possible," says Becker.


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    http://www.betterhumans.com/News/new...D=2003-11-04-2

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    Gel that heals wounds faster developed

    Gel that heals wounds faster developed

    ANI[ SATURDAY, NOVEMBER 08, 2003 09:34:06 PM ]

    LONDON: British scientists have developed a gel that heals wounds in half the time compared to any other gel.




    The gel, called Nexagon, works by speeding up the rate of wound closure and reducing inflammation.



    University College London researchers have received an award for the gel at the Medical Futures Innovation Awards. Although the gel still needs to go through clinical trials, they believe it could transform treatment for millions of people in just a few years.



    Laboratory tests on animals have shown that an ordinary cut that would normally take about a week to close heals in three days with the gel, says a BBC report.



    It has proved effective on skin, brain tissue, the cornea in the eye and even with injury to the spinal cord.



    The scientists believe it will have a wide range of potential applications. They say it could benefit patients undergoing cosmetic surgery, those with chronic wounds or spinal injuries.



    In particular, they believe elderly people could benefit from the gel, as they are more prone to slow healing wounds and infection.




    http://timesofindia.indiatimes.com/c...ow?msid=273720
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    Another bridge?!

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