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Thread: New Procedure Repairs Severed Nerves in Minutes, Restoring Limb Use in Days or Weeks

  1. #1
    Senior Member patecatl's Avatar
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    New Procedure Repairs Severed Nerves in Minutes, Restoring Limb Use in Days or Weeks

    ScienceDaily (Feb. 3, 2012) — American scientists believe a new procedure to repair severed nerves could result in patients recovering in days or weeks, rather than months or years. The team used a cellular mechanism similar to that used by many invertebrates to repair damage to nerve axons.

    http://www.sciencedaily.com/releases...0203092423.htm

    Their results were recently published in the Journal of Neuroscience Research.

    "We have developed a procedure which can repair severed nerves within minutes so that the behavior they control can be partially restored within days and often largely restored within two to four weeks," said Professor George Bittner from the University of Texas. "If further developed in clinical trials this approach would be a great advance on current procedures that usually imperfectly restore lost function within months at best."

    The team studied the mechanisms all animal cells use to repair damage to their membranes and focused on invertebrates, which have a superior ability to regenerate nerve axons compared to mammals. An axon is a long extension arising from a nerve cell body that communicates with other nerve cells or with muscles.

  2. #2
    peripheral nervous system?

  3. #3
    simply wow!!

  4. #4
    I would love to read the original research papers. If anyone has access, please forward it to me.

    http://onlinelibrary.wiley.com/doi/1...657602A.d03t04

    Thanks for posting patecatl!

  5. #5
    PEG is old as F@#$, but we must not try it in humans, status quo is at stake!
    http://www.youtube.com/watch?v=gGuYUoijwOQ

  6. #6
    Those videos were from 2001

  7. #7
    Quote Originally Posted by Dmitriy View Post
    PEG is old as F@#$, but we must not try it in humans, status quo is at stake!
    http://www.youtube.com/watch?v=gGuYUoijwOQ
    PEG?
    I don't see anything that indicates that this is the same type of research, besides in dealing with SCI or PNI.

    Anyone up on this?

  8. #8
    Senior Member cypresss's Avatar
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    Not the original article, but with valuable details.

    "Professor Bittner's team had discovered earlier that when a plasma membrane is damaged, a calcium-mediated healing mechanism starts to draw small vesicles toward the site of the injury. Vesicles are small sacks made of lipid membranes which provide the material needed to repair an injured plasma membrane. However, when the vesicles are attracted to the site of a severed axon, both ends of the axon are sealed off by this repair mechanism, preventing regrowth of the nerve.

    To avoid this problem, the first step of the Texas group's nerve repair procedure is to bathe the area of the severed nerve with a calcium-free saline solution. By removing calcium from the injured axons, premature healing of the axon ends by this vesicle-based repair mechanism is prevented and even reversed. The damaged axons remain open, and can more easily be reattached. The calcium-free solution also contains antioxidants (e.g., methylene blue) to prevent degenerative changes in the axon and nerve
    " [source]

    sounds beautiful but: "While the procedure developed by Bittner's group will not apply to the central nervous system or spinal cord injuries, the procedure offers hope to people whose futures include accidents involving damaged nerves."
    Last edited by cypresss; 02-08-2012 at 07:41 AM.
    This signature left intentionally blank.

  9. #9
    Quote Originally Posted by Dmitriy View Post
    PEG is old as F@#$, but we must not try it in humans, status quo is at stake!
    http://www.youtube.com/watch?v=gGuYUoijwOQ


    That is where we went Wong . Should have being born with 4 legs and a tale
    AS I SIT HERE IN MY CHAIR . I LOOK OUT UPON THE GROUND .I WONDER WILL I EVER GET UP AND WALK A ROUND ??


    http://justadollarplease.org

  10. #10
    Quote Originally Posted by cypresss View Post
    sounds beautiful but: "While the procedure developed by Bittner's group will not apply to the central nervous system or spinal cord injuries, the procedure offers hope to people whose futures include accidents involving damaged nerves."
    This sounds a little better: "Baby steps is the nature of the business," said English. "Right now we are in mammals. We are going to move it right from the sciatic nerve and peripheral nerve into the spinal cord and keep pushing until we go all the way."
    http://www.khou.com/news/UT-research...138860469.html

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