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Thread: State of Human Trials

  1. #51
    Senior Member Schmeky's Avatar
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    Summary of cutting edge human trials:

    1) Lima in Portugal, nasal mucosa
    2) Brisbane Australia, autologous OEG
    3) Huang, Beijing, fetal OEG
    4) Tarcisio Barros, Brazil, bone marrow stem cells
    5) Bruhovetsky, Russia, bone marrow stem cells

    1 through 5 have begun.

    5) Mexico, Rameriz, cord blood stem cells (2003)
    6) China, stem cells, possibly 2004/2005
    7) Geron, stem cells, USA, late 2005, early 2006
    8) Geoff Raisman, UK, OEG, late 2005, early 2006
    9) Almueda Ramon-Cuento, Spain, OEG, late 2005, early 2006

    5 through 9 are scheduled/pending.

    Updated for new members/visitors.

  2. #52
    These lists are great. Next we can begin noting which are excepting patients for treatment or participation which would include many of our members. I believe there are currently two locations that anyone here can possibly go to. A long way from a few years ago. Thanks Dr Young, Dr McDonald and all the rest.

    [This message was edited by Stew on 07-02-03 at 11:05 PM.]

  3. #53
    Shmeky, since we are adding overseas centers including ones with that are touting treatments with relatively limited scientific evidence, perhaps I can add to your list.

    1. Samuel Rabinovich in Novosibirsk has been transplanting fetal "stem cells" into people with brain and spinal cord injury for a number of years.
    2. Zhang in Shanghai has apparently done peripheral nerve bridging between spinal roots above the injury site with bladder, muscle, and other organs in several hundred patients.
    3. Carl Kao is continuing to decompress, implant peripheral nerves, and omentum transplants to spinal cord of people with chronic spinal cord injury.
    4. Henreich Cheng in Taipei is doing peripheral nerve bridges across the injury site combined with a growth factor cocktail.

    In addition, there are several ongoing trials in the U.S.
    1. Purdue University is doing alternating current stimulation in patients with subacute spinal cord injury.
    2. The Diacrin-sponsored porcine fetal stem cell trials is winding down and I am not sure what the results are but it is being done at Washington University in St. Louis and in Albany Medical Center in Albany (NY).
    3. Acorda Therapeutics 4-AP trial at 72 centers in the U.S. and Canada.

    Wise.

  4. #54
    Senior Member Schmeky's Avatar
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    Summary of cutting edge human trials:

    1) Lima in Portugal, nasal mucosa
    2) Brisbane Australia, Autologous OEG
    3) Huang, Beijing, fetal OEG
    4) Tarcisio Barros, Brazil, Autologous Bone Marrow Stem Cells
    5) Bruhovetsky, Russia, bone marrow stem cells

    1 through 5 have begun. If any members have any info on these please post accordingly.

    6) Mexico, Rameriz, cord blood stem cells (2003)
    7) China, stem cells, possibly 2004/2005
    8) Geron, stem cells, USA, late 2005, early 2006
    9) Geoff Raisman, UK, OEG, late 2005, early 2006
    10) Almueda Ramon-Cuento, Spain, OEG, late 2005, early 2006
    11) Tulane Med. Ctr., Autologous Bone Marrow Stem Cells, USA, Mid-2004

    6 through 11 are scheduled/pending.

    Updated for new members/visitors.

  5. #55
    Senior Member KIM's Avatar
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    ¿How about some results?

  6. #56
    Senior Member chastev8's Avatar
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    What about Prockop's group planning a clinical trial to treat patients with spinal cord injuries. It is scheduled to take place in June of 2004

  7. #57
    Kim

    results - there's a radical idea. We have to wait for years just for the Phase 1 safety tests to be done

  8. #58
    Senior Member KIM's Avatar
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    Chris2

    We already know that it´s safe, no death reported so far or other complications, neither if improvement came along. I´m afraid secrecy means failure, and if something really works please don´t treat us little kids that have to wait till xmas to open their presents . We all know how the business runs.

  9. #59
    question for Dr.Young

    as i mentioned earlier in my post, my son is a T4-5 Asia A. his spinal cord is severed.
    i have a two part question:
    i have been reading a lot about the regeneration trials, and it seems that so far those who are in my son's cathegory, do not qualify for it.
    do you know if there are any trials with severed spinal cords?
    also at the T3 level there are one or two tiny bullet fregments in the spinal canal. at the moment they are just sitting there. i would like to know, in your oppinion is there a chance that those fragments would move and cause more damage to the spinal cord at that level? or are they stable?

    take care
    andrea

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