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Thread: W2W a few weeks later

  1. #21
    redundant because a cure has been found I mean

  2. #22
    Senior Member lunasicc42's Avatar
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    Quote Originally Posted by Christopher Paddon View Post
    redundant because a cure has been found I mean

    What cure has been found?
    "That's not smog! It's SMUG!! " - randy marsh, southpark

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  3. #23
    Quote Originally Posted by KofQ View Post
    There are several trials for chronic injuries. You are just not aware of them.
    http://unite2fightparalysis.org/clinicaltrials



    I think that many people would agree that Paolo's understanding of the situation is quite clear. If you are concerned about people getting their facts straight before making inaccurate statements, please refer to your quote regarding chronic trials referenced above.



    I would bet a lot of money that Dr. Silver's research gets to clinical trials on chronic injuries before anything coming from MP. To think what he or Wise or a few other more promising researchers could have accomplished with $250 million. I would probably not be typing this right now. THAT is disheartening.



    If Marc or Rick know how the researchers at their organizations are getting leapfrogged in the race to develop therapies, they would make big changes in the way that money is spent. If they are aware and are either complacent or complicit, that would be beyond the pale



    Millions of people with cancer and HIV are living active and relatively normal lives with relatively normal lifespans. Magic Johnson, Greg Louganis, Lance Armstrong, Sheryl Crow, Scott Hamilton, the list goes on and on. To keep promoting organizations like MP or RHF when they have produced almost no tangible results is illogical.




    That was just so asinine that it deserved a second read...



    Not to defend CDRF, but they only spend 12.4% of their income on fund raising. MP spends 26.9%
    http://www.charitynavigator.org/inde...summary&orgid=5066
    http://www.charitynavigator.org/inde...ary&orgid=7876
    And are you suggesting that one should aspire to the "success" that is the Miami Project or RHF? People should be encouraged to donate to the most promising researchers, not the ones with the best poster boys.


    If people did this MP and RHF would not be operating right now.
    Right on ! tell him brother !!!
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  4. #24
    I mean that W2W's purpose should be to make itself redundant as soon as possible by finding a cure

    It should not perpetuate itself into a neverending series of rallies that exists for its own sake (which many of us think some charities do)

  5. #25
    Quote Originally Posted by LetsGo View Post
    Paolo, with all due respect.............
    When a post start this way it doen't look very promising..

    Paolo
    In God we trust; all others bring data. - Edwards Deming

  6. #26
    Quote Originally Posted by LetsGo View Post
    ..... What you are referencing is Dr. Dietrich saying that the first patients for the Schwann cell trial will be on acutes. That does not mean they are not conducting research on chronic injuries. THEY ARE.
    Really?? Please let me know what, I'll be happy if you can prove me wrong.

    Why did they do all the preclincal work with schwann cells on acute SCI instead of chronic SCI?

    They could have done the preclinical work on rats 3 months after SCI and now go to clinical trials on chronic SCI as all of us are chronic.

    Does that make sense to you?

    Paolo
    In God we trust; all others bring data. - Edwards Deming

  7. #27
    Quote Originally Posted by LetsGo View Post

    .....Dr. Dietrich said they will also be conducting the schwann cell trials on chronic injuries, just not until the first 8-10 acute patients have been treated. Just because they are starting with acute injuries doesn't mean that they are not conducting ongoing research on chronic injuries. They have and are. They are testing all types of animal models in both the acute and chronic setting. I think you need to accept that the biology of repairing the nervous system is much more complex than in acutes but that most scientists test their studies in both.
    Ok 8-10 patient with acute SCI plus a few years follow up is going to take many years just to find out that schwann cells are safe but don't improve function in acute SCI.
    Then, maybe, same phase I/II on chronic SCI to prove again schwann cells are safe but not effective in chronic SCI.

    Is that ok for you?

    BTW I hope you know that what I have just said above is based on strong animal data and on a clinical trial on humans.

    Paolo
    In God we trust; all others bring data. - Edwards Deming

  8. #28
    Quote Originally Posted by LetsGo View Post

    Dr. Pearse who is one of the lead scientists on the schwann cell trial research is also conducting research using OEG cells, schwann cells, IL-10, and methylprednisolone specially for chronics. I also know he has aother ongoing studies with different combination approaches to treating chronic injuries. Again - just because the surgeries are starting with acute doesn't mean chronic research isn't ongoing.
    Please tell me more about all this exciting research that dr. Perse is doing, I can't wait to hear more!

    and once again, please explain me why firs acute and then chronic?

    I don't get it. Let's do first chronic then we move on acute SCI.

    Paolo
    In God we trust; all others bring data. - Edwards Deming

  9. #29
    Quote Originally Posted by LetsGo View Post

    ....everyone needs to stop bashing The Miami Project and their efforts to begin with actutes. There are no other researchers in the world who are conducting rigerous, published trials that will begin with chronics. If the scientific field worldwide could do this, they would. Obviously there is a reason EVERYONE is starting with acute injuries but that doesn't mean chronic research isn't being done simultaniously.
    Here you prove me that you are not well informed at all.
    I now several researchers that focus mainly on chronic SCI.

    Just think about the Stem Cell Inc. trial, they are doing a clinical trial on people with SCI up to one year post that I would say is chronic SCI.

    The problem is that to set up a chronic SCI study on animals it is more complicated and takes more work and it will probably complicate life of researchers when it comes on plannong their vacations etc..
    Some researchers a little drink told me that

    Then as you may know chronic SCI has some advantages as, for example the injury site is stable and has less variables to isolate..

    So please try with better arguments!

    Paolo
    In God we trust; all others bring data. - Edwards Deming

  10. #30
    Quote Originally Posted by Christopher Paddon View Post
    I mean that W2W's purpose should be to make itself redundant as soon as possible by finding a cure

    It should not perpetuate itself into a neverending series of rallies that exists for its own sake (which many of us think some charities do)
    Chris, it would be helpful if you went on our website and signed up for our newsletters. You would be better informed of our work. U2FP hasn't held a rally since March 2007.

    If you have any thoughts you would like to share with us, please send them to donna@unite2fightparalysis.org We're always open to hearing from the community that we are dedicated to helping.
    "Our lives begin to end the day
    we become silent about things that matter."
    - Martin Luther King Jr

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