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Thread: Spinal Cord Injury Articles Posted by Manouli

  1. #881
    Asterias Biotherapeutics Announces Treatment of First Spinal Cord Injury Patient with Maximum Dose of AST-OPC1 in SCiStar Clinical Trial
    November 8, 2016
    -Complete cervical spinal cord injury patient (AIS-A) has for the first time received maximum 20 million cell dose of AST-OPC1-
    -Enrollment and dosing of patients with incomplete cervical spinal cord injuries (AIS-B) continues; second AIS-B patient recently dosed with 10 million cells-
    FREMONT, Calif. – Nov. 8, 2016 – Asterias Biotherapeutics, Inc. (NYSE MKT: AST), a biotechnology company pioneering the field of regenerative medicine, today announced that the first patient with complete (AIS-A) cervical spinal cord injury was successfully administered the highest dose of 20 million cells of AST-OPC1 (oligodendrocyte progenitor cells) in the SCiStar clinical trial at Santa Clara Valley Medical Center (SCVMC) in San Jose, CA. In addition, enrollment continues in the AIS-B 10 million cell cohort with a second patient now dosed.
    more...
    http://asteriasbiotherapeutics.com/a...linical-trial/

  2. #882
    Asterias Biotherapeutics Inc (AST) Stock Rips Higher
    Published on November 14, 2016 at 9:35 am by Joshua Rodriguez in News,Stock Analysis
    Asterias Biotherapeutics Inc (NYSEMKT:AST) is continuing to trade higher, tacking on an additional 22% gain to its share price on Friday, pushing its gains for the week to 40%.
    AST is expected to release earnings this afternoon, however, investors appear to be looking past those numbers and are focused on the news that AST has treated its first patient in itsdose escalation SciStar clinical trial, treating patients with complete cervical spinal cord injury.
    read....
    http://www.insidermonkey.com/blog/as...higher-487554/

  3. #883
    Chinese doctors fix animal spinal cord injuries
    Updated 2016-11-25 16:32:19 Xinhua

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    A team of Chinese doctors has claimed success in fixing spinal cord injuries in animals.
    "We used polyethylene glycol (PEG) compounds to stimulate the injured nerve cells to regenerate. Previous tests on guinea pigs, rats and dogs showed positive results," said Ren Xiaoping, a research fellow with the 2nd Affiliated Hospital of Harbin Medical University in north China's Heilongjiang Province.
    read...
    http://english.china.com/news/china/...25/817978.html

  4. #884
    This is great news. What makes it better is it is even published in US journal.

  5. #885
    Quote Originally Posted by scimike View Post
    This is great news. What makes it better is it is even published in US journal.
    Well, not really so much. To achieve a successful spinal cord anastomosis (an effective technique to assure rapid reinnervation of the body across a divided segment of the CNS) would be mostly impractical for the general population. People don't generally have a clean cut transected cord and a syringe full of PEG handy to immediately glue the cut back together.

    http://www.surgjournal.com/article/S...024-1/fulltext

    Here's another recent thread where they were doing a fast glue on an animal cord transection.

    http://sci.rutgers.edu/forum/showthr...d-spinal-cords
    Last edited by GRAMMY; 11-28-2016 at 05:04 PM.

  6. #886
    GRAMMY, you are right and you make a lot of sense. As usual, I got excited and saw that it was published in US journal and all that. Thank you.

  7. #887
    Precise nerve stimulation via electrode implants offers new hope for paralysis patients

    Tue, 11/22/2016 - 2:31pm /news/2016/11/precise-nerve-stimulation-electrode-implants-offers-new-hope-paralysis-patients
    by Oregon State University
    The work focused on controlling electrical stimulation pulses delivered to peripheral nerve fibers. When a patient is paralyzed, one of the possible causes is damage to the spinal cord, which along with the brain makes up the central nervous system. The brain is working, and so are motor and sensory nerves in the peripheral nervous system, but electrical signals can't flow between those nerves and the brain because of the spinal cord injury.
    more...
    https://www.mdtmag.com/news/2016/11/...lysis-patients

  8. #888
    ?1m grant boosts zebra fish research into paralysis
    A pre-Brexit ?1 million European research grant is to help British scientists investigate a fishy secret that could lead to new treatments for spinal cord injuries.
    The team is looking into the remarkable ability of zebra fish to repair the sort of spinal damage that in humans causes irreversible loss of movement.
    It is hoped the findings will lead to new therapies for spinal injury paralysis, as well as neurodegenerative conditions such as motor neurone disease and multiple sclerosis.
    Specialised microscope techniques will be used to watch the mechanisms of nerve cell repair in action in the fish.
    At the end of the three-year study the researchers hope to have potential treatments that can be taken forward in clinical trials.
    read...

    https://www.eveningexpress.co.uk/pip...nto-paralysis/

  9. #889
    Health News | Mon Dec 5, 2016 | 4:12am EST
    ReNeuron says stem cells improved motor function in stroke study

    n"Biotechnology company ReNeuron Group Plc said its experimental stem cell therapy helped some patients improve motor functions in their arms in a mid-stage study after being disabled by stroke.
    Shares of the company jumped 22 percent to 3.45 pence per share in morning trade on Monday on the London Stock Exchange.
    ReNueron's trial adds to a small but growing number of studies being conducted by a few publicly listed companies around the world that are testing stem cell therapies in various indications.
    Stem cell therapy development has been stalled in the past by stricter regulations in United States, and concerns over side effects in testing a field that experts believe is still in its nascent stages.
    U.S. stem cell therapy developer Asterias Biotherapeutics Inc said in November that an early study of its treatment for complete spinal cord injury hit its efficacy target within three months.

    read more...
    http://www.reuters.com/article/us-re...idUSKBN13U0VG?

  10. #890
    Spinal cord rehabilitation and repair: an interview with Quentin Barraud
    Published on November 15, 2016 at 5:34 AM ? No Comments
    Sponsored Content by Logos Biosystems, Inc.
    insights from industryDr. Quentin BarraudPost-doc at the EPFL
    Interview conducted by James Ives (MPsych)
    Spinal cord repair and rehabilitation is a difficult but important topic to research, can you please give a brief overview of research in this field?
    There are many grades of spinal cord injuries, in terms of range of movement, from small disabilities to becoming wheelchair bound for the rest of your life, the range is very broad.
    There are many different approaches to try to overcome these disabilities, with key areas of research being focussed on developing stem cell therapies and using growth factors to promote regrowth of the nerve tissue after the injury.

    read....
    http://www.news-medical.net/news/201...n-Barraud.aspx

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