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Thread: Spinal Cord Injury Articles Posted by Manouli

  1. #831
    Breakthrough by Hong Kong researchers offers hope people with spinal cord injuries may walk again
    HKUST researchers discover way to regenerate damaged spinal cords of lab mice, offering hope to millions of people with long-term injuries
    PUBLISHED : Wednesday, 22 July, 2015, 3:01pm UPDATED : Thursday, 23 July, 2015, 3:20am
    Ben Westcott
    Millions of people around the world paralysed by spinal cord injuries may one day be able to walk again, following a breakthrough by Hong Kong scientists.
    Researchers at Hong Kong University of Science and Technology led by Professor Kai Liu have discovered a way to regenerate axons, or nerve fibres, in the spinal cords of mice with long-term injuries.
    It's the first time axon regeneration has been induced in the corticospinal tract from injuries at least 12 months old.
    "Considering animal life span is two to three years, roughly one year at this stage is comparable to 25 years in a human, so this means it's possible to be applied [to very old injuries]," Liu said.

  2. #832
    Jul 25, 2015
    Neuralstem Wins Patent Infringement Case Vs. StemCell, Inc.; Moves Forward In Spinal Cord Injury
    Must Read | Jul. 24, 2015 6:15 AM ET | 16 comments | About: Neuralstem, Inc. (CUR), Includes: STEM Subscribers to SA PRO had an early look at this article. Learn more about PRO ?
    Disclosure: I am/we are long CUR. (More...)
    ⦁ Neuralstem won its long-standing patent infringement case vs. StemCells, Inc.
    ⦁ Work continues with NSI-566 in both ALS and SCI.
    ⦁ Anecdotal evidence from one patient in the Phase 1 spinal cord injury trial is encouraging.
    ⦁ I believe the shares are worth $3.50.
    By Jason Napodano, CFA
    On July 23, 2015, Neuralstem, Inc. (NASDAQ:CUR) announced that the U.S. District Court for the District of Maryland dismissed a patent infringement case brought by StemCells, Inc. (NASDAQ:STEM) on July 22, 2015. The case was dismissed with prejudice, meaning StemCells, Inc. cannot appeal the decision. I view this as very good news for Neuralstem, as the StemCells, Inc. patent infringement case was a significant overhang for many investors getting familiar with the Neuralstem story.
    read here...

  3. #833
    Non-surgical approach helps people with paralysis move their legs
    By Stuart Wolpert, UCLAThursday, July 30, 2015
    In a study conducted at UCLA, five men who had been completely paralyzed were able to move their legs in a rhythmic motion thanks to a new, noninvasive procedure that stimulates the spinal cord. It is believed to be the first time voluntary leg movements have ever been relearned in completely paralyzed patients without surgery. The results are reported in the Journal of Neurotrauma.
    “These findings tell us we have to look at spinal cord injury in a new way,” said V. Reggie Edgerton, senior author of the research and a UCLA distinguished professor of integrative biology and physiology, neurobiology and neurosurgery.
    Edgerton said although it likely will be years before the new approaches are widely available, he now believes that it is possible to significantly improve quality of life for patients with severe spinal cord injuries, and to help them recover multiple body functions.
    “People who are paralyzed are often told very early on, ‘Don’t have any hope because you’re not going to recover function below the lesion,’ ” he said. “They have been told that for decades, and still are today. But this was ridiculous before, and it’s even more ridiculous now.”

  4. #834
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  5. #835
    Senior Member Tbone57's Avatar
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  6. #836
    7M awarded to NY teams researching spinal cord injuries
    By Andrew Murphy Published: August 4, 2015, 4:12 am

    ALBANY, N.Y. (AP) – New York health officials say nine research teams at institutions across the state have been awarded $5.7 million toward developing treatments for spinal cord injuries.
    According to the Health Department, about 1,000 New Yorkers suffer traumatic spinal injuries annually, joining nearly 276,000 people living in the U.S. with paralysis.

  7. #837
    Public Release: 13-Aug-2015 Regenerating nerve tissue in spinal cord injuries
    Rush begins participation in novel study using stem cells to treat spinal cord injuries
    Rush University Medical Center
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    Researchers at Rush University Medical Center are exploring a new therapy using stem cells to treat spinal cord injuries within the first 14 to 30 days of injury. Rush is only the second center in the country currently studying this new approach.
    The therapy uses a population of cells derived from human embryonic stem cells containing progenitor cells that support nerve cells and can potentially make poorly functioning nerves function better.
    "There are currently no therapies which successfully reverse the damage seen in the more than 12,000 individuals who suffer a spinal cord injury each year in the United States alone," says Dr. Richard G. Fessler, professor of neurological surgery at Rush University Medical Center and principal investigator for the Phase 1 clinical trial involving AST-OPC1 (oligodendrocyte progenitor cells). An estimated 1.3 million Americans are living with a spinal cord injury.

  8. #838
    Paralyzed Patients Get Reason for Hope with New Study
    Posted by David Mittleman
    August 26, 2015 12:43 PM

    Last month the National Institutes of Health announced the astonishing results of a breakthrough study. According to the NIH, 5 men who were previously completely paralyzed were able to move their legs with the help of noninvasive spinal cord stimulation. The findings of the study surprised even the researchers.
    Epidural spinal cord stimulation itself isn’t new. About four or five years ago, scientists were able to produce similar results in patients by surgically implanting a spinal cord stimulator. The significance of this new study is that the spinal stimulation was noninvasive, reducing the risk of surgical complications that could slow the healing process.
    While we’re not quite on the brink of a complete cure for paralysis, these new developments are incredibly encouraging. It is estimated that about 6 million people in the US are paralyzed – about 1 in 50 individuals. This number is much higher – about 50% higher – than previously thought. Earlier counts had included only central nervous system disorders and excluded other common mobility problems.

  9. #839
    Asterias Biotherapeutics Concludes Recruitment of Initial Safety Cohort of the SCiStar Phase 1/2a Dose-Escalation Clinical Trial of AST-OPC1 for Complete Cervical Spinal Cord Injury

    Date:8/31/2015 [Outline] [RSS & Subscription]

    MENLO PARK, Calif., Aug. 31, 2015 /PRNewswire/ -- Asterias Biotherapeutics, Inc. (NYSE MKT: AST), a biotechnology company focused on the emerging field of regenerative medicine, today announced that the third patient was successfully dosed at Chicago-based Rush University Medical Center in a Phase 1/2a clinical trial evaluating activity of escalating doses of AST-OPC1 (oligodendrocyte progenitor cells) in newly injured patients with sensory and motor complete cervical spinal cord injury (SCI). This represents the final patient treated at the initial low-dose (2 million cells) safety cohort. The results of the study continue to support a robust safety profile for AST-OPC1, with no serious adverse events observed in any of the three treated patients to date.

  10. #840
    Robot Millionaire Takes a Shot at Fixing Severed Spines
    Natasha Khan
    August 31, 2015 — 5:00 PM EDT Updated on August 31, 2015 — 11:33 PM EDT
    On a cloudy Wednesday morning in the Tokyo suburb of Tsukuba, Yoshiyuki Sankai points excitedly to a slide of severed spinal cords. They belong to rats, and he’s used cell technology to help reconnect the nerves.
    A multi-millionaire whose robot company, Cyberdyne Inc., went public last year, Sankai is researching ways to repair damaged body tissue. The 57-year-old scientist’s vision: to treat patients with spinal injuries by using stem-cell related technology to repair nerve connections and robotic suits that aid movement.

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