Spinal Cord Injury Articles Posted by Manouli

[manouli]

I do wish something to happened soon! I want to get up tomorrow and they say this is it, no more paralysis! I keep on dreaming!

[Moe]

I do wish something to happened soon! I want to get up tomorrow and they say this is it, no more paralysis! I keep on dreaming!

Don't worry, nobody's going to shoot the messenger! hehe

dam, I hear you, it would be nice this dream comes true...

[manouli]

Could nose cells treat spinal cord injuries?
August 13, 2018, Science in Public

quote: While the results have been positive for mice, spinal cord injuries in humans are more complex. But this research paves the way for clinical trials anticipated to begin in 2020, using nasal cells from spinal cord injury sufferers and giving hope to many that they may walk again.
read article here:
https://medicalxpress.com/news/2018-...-injuries.html

[NW-Will]

Still dreaming here too... thanks you for all the posts.

[manouli]

Neuroscientists restore significant bladder control to 5 men with spinal cord injuries
Magnetic stimulation of lower spine eliminates need of catheter for up to 4 weeks
Date:
August 22, 2018
Source:
University of California - Los Angeles Health Sciences
Summary:
Magnetic stimulation of the lower spinal cord through the skin enabled five men with spinal-cord injuries to recover significant urination control for up to two weeks. The new approach could enhance patients' quality of life by increasing independence and reducing reliance on a catheter to empty the bladder.
read...
https://www.sciencedaily.com/release...0822082648.htm

[manouli]

Signaling cascade that repairs damaged nerve cells characterized
Date:
August 24, 2018
Source:
Nagoya University
Summary:
Through a study of roundworm nerve cells with severed axons, researchers showed that a signaling cascade that normally functions in promoting the phagocytosis of apoptotic cells also acts in inducing axon regeneration. The findings shed light on a fundamental feature of nerve repair, which is limited in the central nervous system in humans, and thus could pave the way towards treatments for brain and spinal cord injuries.
read...
https://www.sciencedaily.com/release...0824101204.htm

[manouli]

New Study Provides Better Understanding of Potential Regeneration after Brain/Spinal Cord Injury
Researchers at BUSM have uncovered new information on the pathways involved in neuronal regeneration, hopefully bringing the medical community one step closer to managing brain and spinal cord injuries.
By observing neurons after injury, they found that by changing the levels of sugars that cover the surface of proteins (called O-GlcNAc modifications), they could alter neuronal metabolism and thus were able to significantly enhance neuronal regeneration after injury.
Using an experimental model, the researchers compared neurons in which O-GlcNAc levels were either absent or in abundance. The researchers then used a specially designed laser to injure individual neurons and measure subsequent regeneration in each of these conditions.
more..


http://www.bumc.bu.edu/busm/2018/08/...l-cord-injury/

[manouli]

Eusol shares soar on market debut
reporter">By Ted Chen

quote:
Eusol’s pipeline also includes EF135, a recombinant acidic fibroblast growth factor that is being developed for spinal cord injury repair.
Due to EF135’s high development costs, the Eusol is focusing first on the domestic market, but will seek seek distribution partners for other markets further down the line, he said.
read..
http://www.taipeitimes.com/News/biz/.../30/2003699428

[manouli]

Swiss scientists succeed in regenerating nerve fibers across spinal cord injury
Source: Xinhua| 2018-08-30 03:32:38|Editor: yan
\l "\l "\l "\l "\l "
http://www.news.cn/mobile/xhxw/syzt/index.htm http://www.news.cn/mobile/xhxw/syzt/index.htm
GENEVA, Aug. 29 (Xinhua) -- For the first time Swiss scientists and partners have designed a three-stepped recipe for regenerating electro-physiologically active nerve fibers across complete spinal cord lesions in rodents, the Swiss Federal Institute of Technology Lausanne (EPFL) said in a press release on Wednesday.
The adult mammalian body has an incredible ability to heal itself in response to injury. Yet, injuries to the spinal cord lead to devastating conditions, since severed nerve fibers fail to regenerate in the central nervous system. Consequently, the brain's electrical commands about body movement no longer reach the muscles, leading to complete and permanent paralysis.
read....
http://www.xinhuanet.com/english/201..._137428986.htm

[manouli]

Spinal Cord Injury Triple Treatment Promotes Axons to Bridge the Gap

Scientists in the U.S. and Switzerland have identified three sets of factors that can prompt nerve axons to grow across the damage site of spinal cord injuries (SCI) and re-establish electrical connections with nerves on the other side. The researchers hope that if the results in rodents can be replicated in humans it may lead to new treatments that could regenerate nervous system communication in patients with complete SCI.
"The idea was to deliver a sequence of three very different treatments and test whether the combination could stimulate disconnected axons to regrow across the scar in the injured spinal cord," explains research lead Michael Sofroniew, Ph.D., a professor of neurobiology at the David Geffen School of Medicine at the University of California, Los Angeles. "Previous studies had tested each of the three treatments separately, but never together. The combination proved to be the key."
The team, including researchers at Harvard Medical School, and at the Swiss Federal Institute of Technology, reports on its research in Nature, in a paper titled, “Required growth facilitators propel axon regeneration across complete spinal cord injury.”

read...

https://www.genengnews.com/gen-news-...e-gap/81256190